CEP250-AS1

Summary

CEP250-AS1 (CEP250 antisense RNA 1, HGNC:40143) is a long non-coding RNA gene on chromosome 20q11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40143
Approved symbol	CEP250-AS1
Name	CEP250 antisense RNA 1
Location	20q11.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230155
Ensembl biotype	lncRNA
Entrez	102725201
RNAcentral	URS00026A2719 — lncRNA, 5309 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000416260, ENST00000444933, ENST00000453914, ENST00000762848, ENST00000762849, ENST00000762850, ENST00000762851, ENST00000762852, ENST00000762853, ENST00000762854, ENST00000762855, ENST00000762856, ENST00000762857, ENST00000762858

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416260 — 3 exons

Exon	Start	End
ENSE00001624994	35477826	35477945
ENSE00001663670	35476374	35476675
ENSE00003984914	35490856	35490982

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 82.92.

FANTOM5 (CAGE): breadth broad, TPM avg 2.4782 / max 67.7603, expressed in 395 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
187059	2.3891	395
187058	0.0891	49

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.92	gold quality
granulocyte	CL:0000094	82.54	gold quality
spleen	UBERON:0002106	79.96	gold quality
blood	UBERON:0000178	79.92	gold quality
bone marrow cell	CL:0002092	79.59	gold quality
monocyte	CL:0000576	78.95	gold quality
leukocyte	CL:0000738	78.90	gold quality
bone marrow	UBERON:0002371	78.23	gold quality
lymph node	UBERON:0000029	77.11	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.97	gold quality
sural nerve	UBERON:0015488	73.19	gold quality
tonsil	UBERON:0002372	70.76	gold quality
cortical plate	UBERON:0005343	70.48	gold quality
vermiform appendix	UBERON:0001154	68.99	gold quality
ganglionic eminence	UBERON:0004023	66.43	gold quality
muscle tissue	UBERON:0002385	65.91	gold quality
hindlimb stylopod muscle	UBERON:0004252	64.29	gold quality
stromal cell of endometrium	CL:0002255	63.57	gold quality
rectum	UBERON:0001052	63.27	gold quality
skeletal muscle tissue	UBERON:0001134	63.26	gold quality
small intestine	UBERON:0002108	63.01	gold quality
small intestine Peyer’s patch	UBERON:0003454	62.96	gold quality
mucosa of transverse colon	UBERON:0004991	62.06	gold quality
colonic epithelium	UBERON:0000397	61.76	silver quality
right lung	UBERON:0002167	61.40	gold quality
placenta	UBERON:0001987	61.30	gold quality
upper lobe of left lung	UBERON:0008952	60.61	gold quality
duodenum	UBERON:0002114	60.36	gold quality
gall bladder	UBERON:0002110	60.34	gold quality
smooth muscle tissue	UBERON:0001135	60.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.59

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.