CERNA3

Summary

CERNA3 (competing endogenous lncRNA 3 for miR-645, HGNC:53469) is a long non-coding RNA gene on chromosome 8q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53469
Approved symbol	CERNA3
Name	competing endogenous lncRNA 3 for miR-645
Location	8q12.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	CTA
Ensembl gene	ENSG00000253603
Ensembl biotype	lncRNA
Entrez	105375847
RNAcentral	URS0000266792 — lncRNA, 557 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000521403, ENST00000796055, ENST00000796056, ENST00000796057, ENST00000796058, ENST00000796059, ENST00000796060, ENST00000796061, ENST00000796062, ENST00000796063, ENST00000796064

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000521403 — 3 exons

Exon	Start	End
ENSE00004181308	56075007	56075311
ENSE00004181313	56081545	56081877
ENSE00004181314	56074576	56074880

Expression profiles

Bgee: expression breadth broad, 89 present calls, max score 65.52.

Top tissues by expression

89 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ganglionic eminence	UBERON:0004023	65.52	gold quality
stromal cell of endometrium	CL:0002255	53.62	silver quality
prefrontal cortex	UBERON:0000451	53.25	gold quality
islet of Langerhans	UBERON:0000006	51.75	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.64	gold quality
monocyte	CL:0000576	50.21	silver quality
gall bladder	UBERON:0002110	49.90	gold quality
calcaneal tendon	UBERON:0003701	49.24	silver quality
blood	UBERON:0000178	49.10	silver quality
muscle of leg	UBERON:0001383	48.80	gold quality
endometrium	UBERON:0001295	48.36	silver quality
smooth muscle tissue	UBERON:0001135	47.97	gold quality
heart left ventricle	UBERON:0002084	47.70	gold quality
gastrocnemius	UBERON:0001388	47.68	silver quality
heart	UBERON:0000948	47.28	gold quality
left adrenal gland cortex	UBERON:0035825	46.47	gold quality
kidney	UBERON:0002113	46.45	gold quality
right atrium auricular region	UBERON:0006631	45.95	gold quality
right lobe of liver	UBERON:0001114	45.46	silver quality
small intestine	UBERON:0002108	45.26	gold quality
left adrenal gland	UBERON:0001234	44.90	gold quality
tibial artery	UBERON:0007610	44.20	silver quality
popliteal artery	UBERON:0002250	44.06	silver quality
cerebral cortex	UBERON:0000956	43.69	gold quality
Ammon’s horn	UBERON:0001954	43.32	gold quality
small intestine Peyer’s patch	UBERON:0003454	43.11	gold quality
right hemisphere of cerebellum	UBERON:0014890	42.94	silver quality
ascending aorta	UBERON:0001496	42.89	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	42.70	gold quality
cerebellar hemisphere	UBERON:0002245	42.67	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.