CFAP418-AS1

Summary

CFAP418-AS1 (CFAP418 antisense RNA 1, HGNC:50444) is a long non-coding RNA gene on chromosome 8q22.1.

Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translation.

Source: NCBI Gene 100616530 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50444
Approved symbol	CFAP418-AS1
Name	CFAP418 antisense RNA 1
Location	8q22.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	tospeak
Ensembl gene	ENSG00000253773
Ensembl biotype	lncRNA
Entrez	100616530
RNAcentral	URS000075B725 — lncRNA, 600 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 36 — 36 lncRNA

ENST00000517437, ENST00000517655, ENST00000519366, ENST00000521905, ENST00000655917, ENST00000663556, ENST00000664790, ENST00000671532, ENST00000692571, ENST00000701037, ENST00000777034, ENST00000777035, ENST00000777036, ENST00000777037, ENST00000777038, ENST00000777039, ENST00000777040, ENST00000777041, ENST00000777042, ENST00000777043, ENST00000777044, ENST00000777045, ENST00000777046, ENST00000777047, ENST00000777048, ENST00000777049, ENST00000777050, ENST00000777051, ENST00000777052, ENST00000777053, ENST00000777054, ENST00000777055, ENST00000777056, ENST00000777057, ENST00000777058, ENST00000777059

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000517437 — 5 exons

Exon	Start	End
ENSE00002099544	95610664	95610697
ENSE00002100857	95432626	95432780
ENSE00002114161	95800496	95800655
ENSE00004145344	95268813	95268890
ENSE00004145374	95810019	95810145

Expression profiles

Bgee: expression breadth ubiquitous, 127 present calls, max score 84.94.

FANTOM5 (CAGE): breadth broad, TPM avg 1.5578 / max 42.2922, expressed in 709 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
89826	1.4580	689
89827	0.0998	41

Top tissues by expression

127 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.94	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.52	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	67.02	gold quality
ganglionic eminence	UBERON:0004023	65.02	gold quality
ventricular zone	UBERON:0003053	65.00	gold quality
sural nerve	UBERON:0015488	64.64	gold quality
skeletal muscle tissue	UBERON:0001134	64.03	gold quality
muscle tissue	UBERON:0002385	63.10	gold quality
cortical plate	UBERON:0005343	62.85	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.52	gold quality
monocyte	CL:0000576	62.39	gold quality
calcaneal tendon	UBERON:0003701	62.09	gold quality
islet of Langerhans	UBERON:0000006	59.65	gold quality
bone marrow	UBERON:0002371	59.53	gold quality
amygdala	UBERON:0001876	59.23	gold quality
caudate nucleus	UBERON:0001873	59.02	gold quality
kidney	UBERON:0002113	58.64	gold quality
adult mammalian kidney	UBERON:0000082	58.59	gold quality
right uterine tube	UBERON:0001302	58.50	gold quality
right adrenal gland	UBERON:0001233	58.48	gold quality
placenta	UBERON:0001987	58.36	gold quality
right adrenal gland cortex	UBERON:0035827	57.73	gold quality
prefrontal cortex	UBERON:0000451	57.69	gold quality
stromal cell of endometrium	CL:0002255	57.51	gold quality
left adrenal gland cortex	UBERON:0035825	57.37	gold quality
smooth muscle tissue	UBERON:0001135	57.10	gold quality
right coronary artery	UBERON:0001625	57.07	gold quality
tonsil	UBERON:0002372	56.89	gold quality
corpus callosum	UBERON:0002336	56.87	gold quality
left adrenal gland	UBERON:0001234	56.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.