CFAP58-DT

Summary

CFAP58-DT (CFAP58 divergent transcript, HGNC:45243) is a long non-coding RNA gene on chromosome 10q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45243
Approved symbol	CFAP58-DT
Name	CFAP58 divergent transcript
Location	10q25.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	lncITPRIP-1
Ensembl gene	ENSG00000231233
Ensembl biotype	lncRNA
Entrez	100505869
RNAcentral	URS000075DD99 — lncRNA, 1085 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000435434, ENST00000702505

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435434 — 2 exons

Exon	Start	End
ENSE00004120784	104351296	104351927
ENSE00004120786	104353118	104353685

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 81.61.

FANTOM5 (CAGE): breadth broad, TPM avg 0.9990 / max 223.7190, expressed in 191 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
111321	0.4540	136
111319	0.2722	58
111320	0.2542	62
111318	0.0187	5

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
anterior cingulate cortex	UBERON:0009835	81.61	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.76	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.28	silver quality
blood	UBERON:0000178	77.21	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	76.51	gold quality
nucleus accumbens	UBERON:0001882	76.35	gold quality
prefrontal cortex	UBERON:0000451	75.11	gold quality
cerebral cortex	UBERON:0000956	75.03	gold quality
hypothalamus	UBERON:0001898	74.84	gold quality
frontal cortex	UBERON:0001870	74.75	gold quality
right frontal lobe	UBERON:0002810	74.45	gold quality
Brodmann (1909) area 9	UBERON:0013540	74.42	gold quality
amygdala	UBERON:0001876	73.43	gold quality
temporal lobe	UBERON:0001871	73.16	gold quality
superior frontal gyrus	UBERON:0002661	73.16	gold quality
adenohypophysis	UBERON:0002196	72.58	gold quality
pituitary gland	UBERON:0000007	72.31	gold quality
bone marrow cell	CL:0002092	72.01	silver quality
brain	UBERON:0000955	71.49	gold quality
putamen	UBERON:0001874	69.96	gold quality
primary visual cortex	UBERON:0002436	69.77	gold quality
caudate nucleus	UBERON:0001873	69.72	gold quality
cortical plate	UBERON:0005343	69.52	gold quality
leukocyte	CL:0000738	69.02	gold quality
bone marrow	UBERON:0002371	68.98	gold quality
monocyte	CL:0000576	68.88	gold quality
substantia nigra	UBERON:0002038	68.64	gold quality
Ammon’s horn	UBERON:0001954	68.12	gold quality
islet of Langerhans	UBERON:0000006	65.77	gold quality
ganglionic eminence	UBERON:0004023	65.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.