CFLAR-AS1

Summary

CFLAR-AS1 (CFLAR antisense RNA 1, HGNC:14437) is a long non-coding RNA gene on chromosome 2q33.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:14437
Approved symbol	CFLAR-AS1
Name	CFLAR antisense RNA 1
Location	2q33.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226312
Ensembl biotype	lncRNA
Entrez	65072
RNAcentral	URS000075A8C6 — lncRNA, 1041 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 23 — 23 lncRNA

ENST00000415011, ENST00000474886, ENST00000593896, ENST00000594911, ENST00000595372, ENST00000598453, ENST00000598509, ENST00000601974, ENST00000625224, ENST00000625360, ENST00000626311, ENST00000626451, ENST00000627956, ENST00000628309, ENST00000628648, ENST00000628897, ENST00000629553, ENST00000629722, ENST00000629760, ENST00000629993, ENST00000630898, ENST00000631217, ENST00000631232

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415011 — 7 exons

Exon	Start	End
ENSE00001628776	201148734	201148871
ENSE00001631556	201149125	201149200
ENSE00001635091	201157755	201157823
ENSE00001639440	201153311	201153673
ENSE00001712064	201151098	201151259
ENSE00001734462	201149654	201149760
ENSE00001747337	201140289	201140445

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 91.14.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.5026 / max 88.7486, expressed in 167 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
33209	0.1649	69
33212	0.1043	38
33210	0.0851	22
33208	0.0843	30
33211	0.0640	15

Top tissues by expression

244 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	91.14	gold quality
colonic epithelium	UBERON:0000397	88.84	gold quality
sural nerve	UBERON:0015488	87.71	gold quality
calcaneal tendon	UBERON:0003701	84.78	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.53	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.70	gold quality
adrenal tissue	UBERON:0018303	81.62	gold quality
monocyte	CL:0000576	78.66	gold quality
upper lobe of left lung	UBERON:0008952	78.56	gold quality
leukocyte	CL:0000738	78.10	gold quality
right lung	UBERON:0002167	77.12	gold quality
right atrium auricular region	UBERON:0006631	76.53	gold quality
hindlimb stylopod muscle	UBERON:0004252	76.32	gold quality
blood	UBERON:0000178	76.25	gold quality
apex of heart	UBERON:0002098	75.88	gold quality
upper lobe of lung	UBERON:0008948	75.83	gold quality
cardiac atrium	UBERON:0002081	75.61	gold quality
gastrocnemius	UBERON:0001388	75.33	gold quality
muscle of leg	UBERON:0001383	74.79	gold quality
heart left ventricle	UBERON:0002084	74.24	gold quality
left lobe of thyroid gland	UBERON:0001120	73.64	gold quality
cardiac ventricle	UBERON:0002082	73.10	gold quality
heart	UBERON:0000948	72.49	gold quality
thyroid gland	UBERON:0002046	72.44	gold quality
omental fat pad	UBERON:0010414	72.44	gold quality
peritoneum	UBERON:0002358	72.35	gold quality
spleen	UBERON:0002106	71.83	gold quality
right lobe of thyroid gland	UBERON:0001119	71.59	gold quality
tibial nerve	UBERON:0001323	71.49	gold quality
minor salivary gland	UBERON:0001830	71.49	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	9.53

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.