CHAER1

Summary

CHAER1 (cardiac hypertrophy associated epigenetic regulator 1, HGNC:53620) is a long non-coding RNA gene on chromosome 4q12.

Predicted to be involved in several processes, including cardiac muscle hypertrophy in response to stress; epigenetic regulation of gene expression; and protein-RNA complex assembly. Predicted to be part of ESC/E(Z) complex. Predicted to be active in nucleus.

Source: NCBI Gene 105377667 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53620
Approved symbol	CHAER1
Name	cardiac hypertrophy associated epigenetic regulator 1
Location	4q12
Locus type	RNA, long non-coding
Status	Approved
Aliases	Chaer
Ensembl gene	ENSG00000288944
Ensembl biotype	lncRNA
Entrez	105377667
RNAcentral	URS0002A5FCF9 — lncRNA, 1227 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000685954, ENST00000848810, ENST00000848811, ENST00000848812, ENST00000848813, ENST00000848814, ENST00000848815, ENST00000848816, ENST00000848817, ENST00000848818

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000685954 — 4 exons

Exon	Start	End
ENSE00003928923	56703571	56703746
ENSE00003930317	56701545	56702117
ENSE00003935459	56702314	56702402
ENSE00004278640	56703841	56704229

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.