CHL1-AS2

Summary

CHL1-AS2 (CHL1 antisense RNA 2, HGNC:40147) is a long non-coding RNA gene on chromosome 3p26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40147
Approved symbol	CHL1-AS2
Name	CHL1 antisense RNA 2
Location	3p26.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224318
Ensembl biotype	lncRNA
Entrez	101927174
RNAcentral	URS0000A76B17 — lncRNA, 742 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 13 lncRNA, 1 retained_intron

ENST00000444879, ENST00000451839, ENST00000452919, ENST00000657108, ENST00000663345, ENST00000756999, ENST00000757000, ENST00000757001, ENST00000757002, ENST00000757003, ENST00000757004, ENST00000757005, ENST00000757006, ENST00000757007

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000444879 — 4 exons

Exon	Start	End
ENSE00001599012	196456	196508
ENSE00001633147	195758	195914
ENSE00001646108	196967	197199
ENSE00001648507	195996	196040

Expression profiles

Bgee: expression breadth ubiquitous, 170 present calls, max score 96.28.

Top tissues by expression

247 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right atrium auricular region	UBERON:0006631	96.28	gold quality
cardiac atrium	UBERON:0002081	94.35	gold quality
tibial nerve	UBERON:0001323	89.16	gold quality
apex of heart	UBERON:0002098	86.95	gold quality
heart left ventricle	UBERON:0002084	86.34	gold quality
cardiac ventricle	UBERON:0002082	84.81	gold quality
cortical plate	UBERON:0005343	84.78	gold quality
endothelial cell	CL:0000115	83.70	silver quality
heart	UBERON:0000948	83.48	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.39	gold quality
sural nerve	UBERON:0015488	82.65	gold quality
anterior cingulate cortex	UBERON:0009835	82.43	gold quality
hypothalamus	UBERON:0001898	81.47	gold quality
amygdala	UBERON:0001876	81.43	gold quality
Brodmann (1909) area 9	UBERON:0013540	81.28	gold quality
right frontal lobe	UBERON:0002810	80.98	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	80.46	gold quality
nucleus accumbens	UBERON:0001882	80.41	gold quality
middle temporal gyrus	UBERON:0002771	79.93	silver quality
Brodmann (1909) area 23	UBERON:0013554	79.50	gold quality
caudate nucleus	UBERON:0001873	79.25	gold quality
kidney epithelium	UBERON:0004819	78.63	gold quality
temporal lobe	UBERON:0001871	78.62	gold quality
putamen	UBERON:0001874	78.29	gold quality
neocortex	UBERON:0001950	78.27	gold quality
cerebral cortex	UBERON:0000956	78.22	gold quality
Ammon’s horn	UBERON:0001954	78.18	gold quality
cardiac muscle of right atrium	UBERON:0003379	77.99	gold quality
left ventricle myocardium	UBERON:0006566	77.82	gold quality
substantia nigra	UBERON:0002038	77.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.