CHODL-AS2

Summary

CHODL-AS2 (CHODL antisense RNA 2, HGNC:58357) is a long non-coding RNA gene on chromosome 21q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58357
Approved symbol	CHODL-AS2
Name	CHODL antisense RNA 2
Location	21q21.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227330
Ensembl biotype	lncRNA
Entrez	141369864

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000432412

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000432412 — 5 exons

Exon	Start	End
ENSE00001631862	18024680	18024750
ENSE00001637854	18099933	18100018
ENSE00001682792	18022370	18022442
ENSE00001734485	18034520	18034629
ENSE00001782362	18114767	18114904

Expression profiles

Bgee: expression breadth broad, 74 present calls, max score 81.00.

Top tissues by expression

74 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.00	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.59	gold quality
placenta	UBERON:0001987	69.40	gold quality
bone marrow cell	CL:0002092	66.51	silver quality
prefrontal cortex	UBERON:0000451	61.87	gold quality
corpus callosum	UBERON:0002336	61.64	gold quality
smooth muscle tissue	UBERON:0001135	59.10	gold quality
calcaneal tendon	UBERON:0003701	58.27	gold quality
duodenum	UBERON:0002114	56.64	gold quality
muscle of leg	UBERON:0001383	55.48	gold quality
liver	UBERON:0002107	54.52	gold quality
myometrium	UBERON:0001296	54.34	gold quality
blood	UBERON:0000178	53.88	silver quality
endometrium	UBERON:0001295	51.97	gold quality
descending thoracic aorta	UBERON:0002345	51.58	gold quality
body of pancreas	UBERON:0001150	50.28	gold quality
monocyte	CL:0000576	49.81	silver quality
gastrocnemius	UBERON:0001388	48.96	gold quality
rectum	UBERON:0001052	48.38	gold quality
thoracic mammary gland	UBERON:0005200	48.18	silver quality
small intestine	UBERON:0002108	48.05	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	46.91	gold quality
prostate gland	UBERON:0002367	46.30	gold quality
tibial artery	UBERON:0007610	46.16	gold quality
heart	UBERON:0000948	45.75	silver quality
thoracic aorta	UBERON:0001515	45.71	gold quality
ascending aorta	UBERON:0001496	45.39	gold quality
frontal cortex	UBERON:0001870	45.25	gold quality
lower esophagus muscularis layer	UBERON:0035833	45.01	gold quality
intestine	UBERON:0000160	44.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.