CISTR

Summary

CISTR (chondrogenesis-associated transcript, HGNC:49426) is a long non-coding RNA gene on chromosome 12q13.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49426
Approved symbol	CISTR
Name	chondrogenesis-associated transcript
Location	12q13.13
Locus type	RNA, long non-coding
Status	Approved
Aliases	CISTR-ACT, CISTRACT, re52431
Ensembl gene	ENSG00000260492
Ensembl biotype	lncRNA
Entrez	102216268
RNAcentral	URS000075EA90 — lncRNA, 856 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 51 — 51 lncRNA

ENST00000570015, ENST00000626733, ENST00000663667, ENST00000669269, ENST00000718025, ENST00000718026, ENST00000718027, ENST00000718028, ENST00000718029, ENST00000718030, ENST00000718031, ENST00000820127, ENST00000820128, ENST00000820129, ENST00000820130, ENST00000820131, ENST00000820132, ENST00000820133, ENST00000820134, ENST00000820135, ENST00000820136, ENST00000820137, ENST00000820138, ENST00000820139, ENST00000820140, ENST00000820141, ENST00000820142, ENST00000820143, ENST00000820144, ENST00000820145, ENST00000820146, ENST00000820147, ENST00000820148, ENST00000820149, ENST00000820150, ENST00000820151, ENST00000820152, ENST00000820153, ENST00000820154, ENST00000820155, ENST00000820156, ENST00000820157, ENST00000820158, ENST00000820159, ENST00000820160, ENST00000820161, ENST00000820162, ENST00000820163, ENST00000820164, ENST00000820165, ENST00000820166

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000570015 — 2 exons

Exon	Start	End
ENSE00003862221	53755820	53756048
ENSE00003866540	53750582	53750965

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 72.63.

Top tissues by expression

100 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
apex of heart	UBERON:0002098	72.63	gold quality
heart left ventricle	UBERON:0002084	67.69	gold quality
heart	UBERON:0000948	67.36	gold quality
uterine cervix	UBERON:0000002	67.35	silver quality
right atrium auricular region	UBERON:0006631	67.19	gold quality
ventricular zone	UBERON:0003053	64.77	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.54	gold quality
prefrontal cortex	UBERON:0000451	61.15	gold quality
primary visual cortex	UBERON:0002436	60.30	gold quality
tonsil	UBERON:0002372	59.71	silver quality
ganglionic eminence	UBERON:0004023	59.33	gold quality
cortical plate	UBERON:0005343	59.12	silver quality
frontal cortex	UBERON:0001870	59.05	gold quality
superior frontal gyrus	UBERON:0002661	57.30	gold quality
cerebral cortex	UBERON:0000956	57.19	gold quality
temporal lobe	UBERON:0001871	56.56	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	56.56	gold quality
amygdala	UBERON:0001876	56.54	gold quality
right frontal lobe	UBERON:0002810	56.50	gold quality
islet of Langerhans	UBERON:0000006	56.29	gold quality
anterior cingulate cortex	UBERON:0009835	56.00	gold quality
cerebellum	UBERON:0002037	55.31	gold quality
cerebellar cortex	UBERON:0002129	55.25	gold quality
cerebellar hemisphere	UBERON:0002245	55.19	gold quality
right hemisphere of cerebellum	UBERON:0014890	55.16	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	55.10	gold quality
brain	UBERON:0000955	55.01	gold quality
Brodmann (1909) area 9	UBERON:0013540	54.23	gold quality
Ammon’s horn	UBERON:0001954	54.06	gold quality
substantia nigra	UBERON:0002038	53.21	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.64

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.