CLMAT3

Summary

CLMAT3 (colorectal liver metastasis associated transcript 3, HGNC:52287) is a long non-coding RNA gene on chromosome 5q33.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52287
Approved symbol	CLMAT3
Name	colorectal liver metastasis associated transcript 3
Location	5q33.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	SPARC-AS1
Ensembl gene	ENSG00000249035
Ensembl biotype	lncRNA
Entrez	101927096
RNAcentral	URS0000082D09 — lncRNA, 1973 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000510576, ENST00000518905, ENST00000663441, ENST00000718194, ENST00000718195, ENST00000718196, ENST00000720521, ENST00000720522

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000510576 — 5 exons

Exon	Start	End
ENSE00002018969	151686382	151687910
ENSE00002047904	151676945	151677047
ENSE00002050119	151685829	151685951
ENSE00002072388	151679656	151679756
ENSE00002075709	151679220	151679336

Expression profiles

Bgee: expression breadth ubiquitous, 154 present calls, max score 92.71.

Top tissues by expression

243 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.71	gold quality
colonic epithelium	UBERON:0000397	72.87	silver quality
stromal cell of endometrium	CL:0002255	71.59	gold quality
sural nerve	UBERON:0015488	70.01	gold quality
sperm	CL:0000019	69.50	gold quality
descending thoracic aorta	UBERON:0002345	64.63	gold quality
bone marrow cell	CL:0002092	64.25	silver quality
granulocyte	CL:0000094	64.13	gold quality
calcaneal tendon	UBERON:0003701	64.00	gold quality
adrenal tissue	UBERON:0018303	63.62	gold quality
thoracic aorta	UBERON:0001515	63.32	gold quality
ascending aorta	UBERON:0001496	63.24	gold quality
popliteal artery	UBERON:0002250	63.18	gold quality
tibial artery	UBERON:0007610	63.17	gold quality
aorta	UBERON:0000947	63.10	gold quality
leukocyte	CL:0000738	63.08	gold quality
monocyte	CL:0000576	62.94	gold quality
right coronary artery	UBERON:0001625	61.85	gold quality
ganglionic eminence	UBERON:0004023	60.70	gold quality
left coronary artery	UBERON:0001626	60.59	gold quality
cortical plate	UBERON:0005343	60.31	gold quality
hindlimb stylopod muscle	UBERON:0004252	60.06	gold quality
coronary artery	UBERON:0001621	59.58	gold quality
gall bladder	UBERON:0002110	59.21	gold quality
endothelial cell	CL:0000115	58.92	gold quality
mucosa of stomach	UBERON:0001199	58.75	gold quality
smooth muscle tissue	UBERON:0001135	58.68	gold quality
ventricular zone	UBERON:0003053	58.21	silver quality
subcutaneous adipose tissue	UBERON:0002190	58.03	gold quality
skin of leg	UBERON:0001511	57.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.87

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.