CLMN

Summary

CLMN (calmin, HGNC:19972) is a protein-coding gene on chromosome 14q32.13, encoding Calmin (Q96JQ2).

Predicted to enable actin filament binding activity. Predicted to be involved in negative regulation of cell population proliferation. Predicted to act upstream of or within neuron projection development. Predicted to be located in membrane. Predicted to be part of meiotic nuclear membrane microtubule tethering complex. Predicted to be active in cytoplasm and nuclear outer membrane.

Source: NCBI Gene 79789 — RefSeq curated summary.

At a glance

• GWAS associations: 10
• Clinical variants (ClinVar): 220 total
• MANE Select transcript: NM_024734

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:19972
Approved symbol	CLMN
Name	calmin
Location	14q32.13
Locus type	gene with protein product
Status	Approved
Aliases	FLJ12383, KIAA1188, KIAA0500
Ensembl gene	ENSG00000165959
Ensembl biotype	protein_coding
OMIM	611121
Entrez	79789

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 6 protein_coding, 3 retained_intron, 1 nonsense_mediated_decay, 1 protein_coding_CDS_not_defined

ENST00000298912, ENST00000553733, ENST00000555336, ENST00000555615, ENST00000556416, ENST00000556441, ENST00000556454, ENST00000557215, ENST00000557696, ENST00000869560, ENST00000941995

RefSeq mRNA: 1 — MANE Select: NM_024734 NM_024734

CCDS: CCDS9933

Canonical transcript exons

ENST00000298912 — 13 exons

Exon	Start	End
ENSE00001098464	95215641	95215733
ENSE00001098491	95221691	95221774
ENSE00001098542	95213219	95213409
ENSE00001168923	95210686	95210879
ENSE00001312578	95181940	95191732
ENSE00001327160	95319711	95319908
ENSE00003463993	95230072	95230133
ENSE00003507005	95223760	95223855
ENSE00003526953	95196498	95196694
ENSE00003531313	95194536	95194596
ENSE00003576300	95202838	95204463
ENSE00003628404	95209395	95209477
ENSE00003629809	95193849	95193919

Expression profiles

Bgee: expression breadth ubiquitous, 275 present calls, max score 98.86.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 9.9064 / max 291.2049, expressed in 1232 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
144783	8.1433	1180
144782	1.5792	610
144784	0.1839	81

Top tissues by expression

294 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	98.86	gold quality
male germ cell	CL:0000015	96.79	gold quality
lateral nuclear group of thalamus	UBERON:0002736	96.54	gold quality
bronchial epithelial cell	CL:0002328	95.85	gold quality
left testis	UBERON:0004533	95.58	gold quality
right testis	UBERON:0004534	95.48	gold quality
renal medulla	UBERON:0000362	94.75	gold quality
epithelium of bronchus	UBERON:0002031	94.61	gold quality
corpus callosum	UBERON:0002336	94.35	gold quality
sural nerve	UBERON:0015488	94.14	gold quality
bronchus	UBERON:0002185	94.12	gold quality
mucosa of paranasal sinus	UBERON:0005030	93.28	gold quality
testis	UBERON:0000473	93.27	gold quality
mucosa of sigmoid colon	UBERON:0004993	92.81	gold quality
colonic mucosa	UBERON:0000317	92.37	gold quality
body of pancreas	UBERON:0001150	92.11	gold quality
dorsal plus ventral thalamus	UBERON:0001897	91.73	gold quality
metanephros cortex	UBERON:0010533	90.96	gold quality
dorsal motor nucleus of vagus nerve	UBERON:0002870	90.70	gold quality
globus pallidus	UBERON:0001875	90.58	gold quality
inferior vagus X ganglion	UBERON:0005363	90.44	gold quality
medial globus pallidus	UBERON:0002477	90.34	gold quality
buccal mucosa cell	CL:0002336	90.21	gold quality
nephron tubule	UBERON:0001231	89.99	gold quality
pancreas	UBERON:0001264	89.70	gold quality
inferior olivary complex	UBERON:0002127	89.64	gold quality
kidney	UBERON:0002113	89.20	gold quality
adult mammalian kidney	UBERON:0000082	89.12	gold quality
subthalamic nucleus	UBERON:0001906	89.10	gold quality
lateral globus pallidus	UBERON:0002476	89.09	gold quality

Single-cell (SCXA)

Detected in 6 experiment(s), a significant marker in 5.

Experiment	Marker?	Max mean expression
E-HCAD-35	yes	72.68
E-ANND-3	yes	14.73
E-CURD-119	yes	14.03
E-GEOD-134144	yes	7.93
E-ENAD-27	yes	7.08
E-CURD-11	no	113.86

Regulation

Is transcription factor: no

miRNA regulators (miRDB)

306 targeting CLMN, top 30 by miRDB confidence (max_score; target_count = how many genes the miRNA targets in total — lower means more specific):

miRNA	Max score	Avg score	miRNA target_count
HSA-MIR-4747-5P	100.00	67.90	2681
HSA-MIR-5196-5P	100.00	67.98	2761
HSA-MIR-4533	100.00	69.48	2758
HSA-MIR-4476	100.00	68.18	2030
HSA-MIR-6876-5P	100.00	67.68	2126
HSA-MIR-4283	100.00	66.42	2097
HSA-MIR-1252-5P	100.00	69.80	2774
HSA-MIR-340-5P	100.00	72.50	4437
HSA-MIR-5692A	100.00	74.40	6850
HSA-MIR-3613-3P	100.00	76.36	7965
HSA-MIR-3925-3P	100.00	69.95	1237
HSA-MIR-4262	100.00	73.26	3931
HSA-MIR-29A-3P	100.00	73.11	1835
HSA-MIR-29B-3P	100.00	73.18	1833
HSA-MIR-29C-3P	100.00	73.15	1833
HSA-MIR-3646	100.00	73.56	5283
HSA-MIR-5193	100.00	67.26	1744
HSA-MIR-3120-5P	100.00	65.56	965
HSA-MIR-4682	100.00	68.89	1258
HSA-MIR-188-3P	100.00	68.76	1240
HSA-MIR-3662	99.99	73.82	5684
HSA-MIR-548AW	99.99	72.57	3559
HSA-MIR-4531	99.99	69.70	3181
HSA-MIR-513B-5P	99.99	69.96	2150
HSA-MIR-196A-1-3P	99.99	72.15	2772
HSA-MIR-548C-3P	99.99	74.01	7587
HSA-MIR-181A-5P	99.99	72.96	2995
HSA-MIR-181B-5P	99.99	72.97	2996
HSA-MIR-181C-5P	99.99	72.95	2996
HSA-MIR-181D-5P	99.99	73.04	2997

Cross-species orthologs

4 orthologs

Organism	Symbol	Gene ID
danio_rerio	clmnb	ENSDARG00000043667
danio_rerio	clmna	ENSDARG00000096867
mus_musculus	Clmn	ENSMUSG00000021097
rattus_norvegicus	Clmn	ENSRNOG00000011044

Paralogs (36): SYNE2 (ENSG00000054654), SPTB (ENSG00000070182), ACTN1 (ENSG00000072110), ACTN2 (ENSG00000077522), DSP (ENSG00000096696), DRP2 (ENSG00000102385), SPTBN1 (ENSG00000115306), MACF1 (ENSG00000127603), FLNC (ENSG00000128591), ACTN4 (ENSG00000130402), SYNE1 (ENSG00000131018), MICAL2 (ENSG00000133816), DTNA (ENSG00000134769), MICAL1 (ENSG00000135596), FLNB (ENSG00000136068), SPTBN5 (ENSG00000137877), DTNB (ENSG00000138101), GAS2L3 (ENSG00000139354), DST (ENSG00000151914), UTRN (ENSG00000152818), SPTBN4 (ENSG00000160460), SPTA1 (ENSG00000163554), PKHD1 (ENSG00000170927), SPTBN2 (ENSG00000173898), SYNE3 (ENSG00000176438), PLEC (ENSG00000178209), SMTNL2 (ENSG00000188176), FLNA (ENSG00000196924), SPTAN1 (ENSG00000197694), DMD (ENSG00000198947), PKHD1L1 (ENSG00000205038), DYTN (ENSG00000232125), MICAL3 (ENSG00000243156), ACTN3 (ENSG00000248746), EPPK1 (ENSG00000261150), GAS2L2 (ENSG00000270765)

Protein

Protein identifiers

Calmin — Q96JQ2 (reviewed: Q96JQ2)

Alternative names: Calponin-like transmembrane domain protein

All UniProt accessions (5): Q96JQ2, G3V3D8, G3V4C0, G3V5E0, G3V5U3

UniProt curated annotations — full annotation on UniProt →

Subcellular location. Membrane.

Tissue specificity. Widely expressed at intermediate level.

RefSeq proteins (1): NP_079010* (*=MANE)

Domains & families (InterPro)

ID	Name	Type
IPR001589	Actinin_actin-bd_CS	Conserved_site
IPR001715	CH_dom	Domain
IPR036872	CH_dom_sf	Homologous_superfamily
IPR047826	CLMN_CH_second	Domain
IPR047827	CLMN_CH_first	Domain
IPR052403	LINC-complex_assoc	Family

Pfam: PF00307

UniProt features (35 total): compositionally biased region 13, modified residue 9, region of interest 6, domain 2, sequence conflict 2, chain 1, transmembrane region 1, sequence variant 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q96JQ2-F1	52.84	0.18

Functional residue map

Curated UniProt residues grouped by drug-discovery relevance — catalytic, ligand-binding, modification, and mutation-validated positions. Source: UniProtKB sequence features.

Post-translational modifications (9): 301, 402, 619, 699, 713, 769, 838, 841, 907

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 187 (showing top): TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN, GOBP_NEUROGENESIS, DELYS_THYROID_CANCER_DN, GOBP_NUCLEUS_LOCALIZATION, CAIRO_HEPATOBLASTOMA_UP, GFI1_01, GOMF_ACTIN_BINDING, NRF2_01, GOBP_CELL_PROJECTION_ORGANIZATION, ROSS_AML_WITH_PML_RARA_FUSION, GOBP_ORGANELLE_LOCALIZATION, chr14q32, YNGTTNNNATT_UNKNOWN, RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN, MULLIGHAN_MLL_SIGNATURE_2_DN

GO Biological Process (3): nuclear migration (GO:0007097), negative regulation of cell population proliferation (GO:0008285), neuron projection development (GO:0031175)

GO Molecular Function (3): actin filament binding (GO:0051015), actin binding (GO:0003779), protein binding (GO:0005515)

GO Cellular Component (4): nuclear outer membrane (GO:0005640), cytoplasm (GO:0005737), meiotic nuclear membrane microtubule tethering complex (GO:0034993), membrane (GO:0016020)

GO top-level categories

Rollup of top GO terms by namespace:

Category	Terms
cellular anatomical structure	2
intracellular transport	1
nucleus localization	1
establishment of organelle localization	1
cell population proliferation	1
regulation of cell population proliferation	1
negative regulation of cellular process	1
neuron development	1
plasma membrane bounded cell projection organization	1
actin binding	1
protein-containing complex binding	1
cytoskeletal protein binding	1
binding	1
nuclear membrane	1
organelle outer membrane	1
nuclear outer membrane-endoplasmic reticulum membrane network	1
intracellular anatomical structure	1
microtubule organizing center attachment site	1
nuclear membrane microtubule tethering complex	1

Protein interactions and networks

STRING

850 interactions, top by confidence (×1000):

Protein A	Protein B	Partner UniProt	Score
CLMN	KIF6	Q6ZMV9	447
CLMN	EFL1	Q7Z2Z2	426
CLMN	EMD	P50402	423
CLMN	AFAP1L2	Q8N4X5	414
CLMN	ERICH6B	Q5W0A0	409
CLMN	NRAP	Q86VF7	409
CLMN	LRRIQ3	A6PVS8	402
CLMN	UBXN7	O94888	396
CLMN	CYP24A1	Q07973	392
CLMN	COPB1	P53618	384
CLMN	TESC	Q96BS2	380
CLMN	STRBP	Q96SI9	378
CLMN	A1CF	Q9NQ94	377
CLMN	SERPINB1	P30740	375
CLMN	FAM234B	A2RU67	372

IntAct

31 interactions, top by confidence:

A	B	Type	Score
CFTR	ESYT2	psi-mi:“MI:2364”(proximity)	0.710
ANXA9	PPL	psi-mi:“MI:0914”(association)	0.660
YWHAG	BLTP3B	psi-mi:“MI:2364”(proximity)	0.640
ADCY9	NEMP1	psi-mi:“MI:0914”(association)	0.640
YWHAH	BLTP3B	psi-mi:“MI:2364”(proximity)	0.570
DYNLT2B	SNX2	psi-mi:“MI:0914”(association)	0.530
HSCB	RBP5	psi-mi:“MI:0914”(association)	0.350
COPB2	ESYT2	psi-mi:“MI:0914”(association)	0.350
CTNNB1	TCERG1	psi-mi:“MI:0914”(association)	0.350
RTN4	ESYT2	psi-mi:“MI:0914”(association)	0.350
UBB	RNF40	psi-mi:“MI:0914”(association)	0.350
AP2M1	C1orf226	psi-mi:“MI:0914”(association)	0.350
FPR1	GPR89A	psi-mi:“MI:0914”(association)	0.350
PPL	UBR5	psi-mi:“MI:0914”(association)	0.350
UBL4B	FECH	psi-mi:“MI:0914”(association)	0.350
CLMN	UQCC4	psi-mi:“MI:0914”(association)	0.350
GPR182	SLC12A8	psi-mi:“MI:0914”(association)	0.350
AP2M1	PER1	psi-mi:“MI:0914”(association)	0.350
SLC67A1	LTN1	psi-mi:“MI:0914”(association)	0.350
SLC2A2	ESYT2	psi-mi:“MI:0914”(association)	0.350
SLC7A11	PSMD9	psi-mi:“MI:0914”(association)	0.350
SLC7A9	CDC7	psi-mi:“MI:0914”(association)	0.350
CANX	ESYT2	psi-mi:“MI:2364”(proximity)	0.270
CDH1	ESYT2	psi-mi:“MI:2364”(proximity)	0.270
SFN	BLTP3B	psi-mi:“MI:2364”(proximity)	0.270
CLMN	FHL1	psi-mi:“MI:0915”(physical association)	0.000

BioGRID (101): CLMN (Proximity Label-MS), CLMN (Affinity Capture-MS), CLMN (Affinity Capture-RNA), CLMN (Affinity Capture-MS), CLMN (Proximity Label-MS), CLMN (Affinity Capture-RNA), CLMN (Protein-RNA), CLMN (Proximity Label-MS), CLMN (Proximity Label-MS), CLMN (Proximity Label-MS), CLMN (Proximity Label-MS), CLMN (Proximity Label-MS), CLMN (Proximity Label-MS), CLMN (Proximity Label-MS), CLMN (Two-hybrid)

ESM2 similar proteins: A0A1B0GVH6, A0A1L8H8C0, A0A1L8HFX9, A0A2R6X6S3, A0JM08, A0MS83, A2BIL8, A2RUV4, E9Q309, F1MCY2, F1QIC4, P46012, Q08D57, Q1LY77, Q498L0, Q4KMC9, Q501J7, Q52KW0, Q5DTJ9, Q5F3P8, Q5RAU1, Q5SW79, Q5T5U3, Q5VT06, Q62417, Q62770, Q66J90, Q69Z38, Q6A065, Q6DFG0, Q6DFV3, Q6FWU4, Q71M21, Q80TN7, Q86TC9, Q8AV28, Q8C5W0, Q8IVL0, Q8IZ21, Q8K0T7

Diamond homologs: A5D7D1, D3ZEN0, D3ZHA0, D3ZHV2, D3ZQL6, E1BBG2, F1MF74, F1RA39, F6QZ15, G3MWR8, G3V7L1, L7UZ85, M9MRD1, O13728, O15020, O43707, O75369, O76329, O88990, O94851, O97592, P05094, P05095, P07751, P11277, P11530, P11531, P11532, P11533, P12814, P13395, P13466, P15508, P16086, P16546, P18091, P20111, P21333, P30427, P35609

SIGNOR signaling

0 interactions.

Enriched among interaction partners

Reactome pathways and GO biological processes over-represented among this gene’s 41 IntAct physical interaction partners (hypergeometric vs the genome-wide background, BH-FDR, gene-set size 15–500, ranked by fold). A functional readout of the neighbourhood — distinct from this gene’s own memberships above, and biased toward well-studied / hub proteins, so read it as themes rather than proof.

Reactome pathways:

Pathway	Partners	Fold	FDR
G2/M Checkpoints	5	21.0×	8e-04
SARS-CoV Infections	5	8.7×	7e-03
Infectious disease	7	5.4×	7e-03

Disease & clinical

Clinical variants and AI predictions

ClinVar

220 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	153
Likely benign	29
Benign	15

Top pathogenic / likely-pathogenic (0)

SpliceAI

2897 predictions. Top by Δscore:

Variant	Effect	Δscore
14:95193321:T:A	donor_gain	1.0000
14:95193330:T:TA	donor_gain	1.0000
14:95194530:A:AC	donor_gain	1.0000
14:95194531:C:CC	donor_gain	1.0000
14:95194531:CTAA:C	donor_gain	1.0000
14:95194532:TAA:T	donor_loss	1.0000
14:95194533:AAC:A	donor_loss	1.0000
14:95194534:A:AC	donor_gain	1.0000
14:95194534:A:C	donor_loss	1.0000
14:95194535:C:A	donor_loss	1.0000
14:95194535:C:CC	donor_gain	1.0000
14:95194592:TAGTC:T	acceptor_gain	1.0000
14:95194594:GTC:G	acceptor_gain	1.0000
14:95194595:TC:T	acceptor_gain	1.0000
14:95194596:CC:C	acceptor_gain	1.0000
14:95194596:CCTGA:C	acceptor_loss	1.0000
14:95194597:C:CC	acceptor_gain	1.0000
14:95196495:TACCT:T	donor_loss	1.0000
14:95196496:AC:A	donor_loss	1.0000
14:95196497:C:G	donor_loss	1.0000
14:95196690:TGGGA:T	acceptor_gain	1.0000
14:95196691:GGGA:G	acceptor_gain	1.0000
14:95196692:GGA:G	acceptor_gain	1.0000
14:95196693:GA:G	acceptor_gain	1.0000
14:95196695:C:CC	acceptor_gain	1.0000
14:95209393:A:AC	donor_gain	1.0000
14:95209394:C:CC	donor_gain	1.0000
14:95209394:CGG:C	donor_gain	1.0000
14:95209399:T:TA	donor_gain	1.0000
14:95209478:C:CC	acceptor_gain	1.0000

AlphaMissense

6681 scored. Top likely-pathogenic:

Variant	Protein change	am_pathogenicity
14:95191620:A:G	W985R	0.999
14:95191620:A:T	W985R	0.999
14:95210845:A:G	W215R	0.999
14:95210845:A:T	W215R	0.999
14:95215669:A:G	L130P	0.999
14:95221713:A:G	L101P	0.999
14:95221739:A:C	F92L	0.999
14:95221739:A:T	F92L	0.999
14:95221741:A:G	F92L	0.999
14:95230095:A:G	W41R	0.999
14:95230095:A:T	W41R	0.999
14:95210836:C:A	G218W	0.998
14:95215664:A:G	W132R	0.998
14:95215664:A:T	W132R	0.998
14:95221704:A:G	L104S	0.998
14:95221734:A:G	L94S	0.998
14:95223806:C:A	G65V	0.998
14:95210835:C:T	G218E	0.997
14:95210843:C:A	W215C	0.997
14:95210843:C:G	W215C	0.997
14:95215702:A:C	I119R	0.997
14:95215702:A:T	I119K	0.997
14:95221706:A:C	F103L	0.997
14:95221706:A:T	F103L	0.997
14:95221708:A:G	F103L	0.997
14:95221725:A:T	I97K	0.997
14:95221727:G:C	N96K	0.997
14:95221727:G:T	N96K	0.997
14:95221740:A:G	F92S	0.997
14:95223806:C:T	G65D	0.997

dbSNP variants (sampled 300 via entrez): RS1000036213 (14:95186546 G>A), RS1000057528 (14:95185419 C>T), RS1000063679 (14:95243977 T>C), RS1000089567 (14:95289743 TG>T), RS1000095017 (14:95193252 A>G), RS1000103571 (14:95306732 A>T), RS1000134013 (14:95214187 A>G,T), RS1000153544 (14:95321038 T>C), RS1000154858 (14:95267655 C>A), RS1000161869 (14:95210914 G>A), RS1000204315 (14:95257164 C>T), RS1000262012 (14:95248624 T>C), RS1000284180 (14:95285560 G>A), RS1000330687 (14:95259241 T>C), RS1000332195 (14:95317476 G>A)

Disease associations

OMIM: gene MIM:611121 | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

10 associations (top):

Study	Trait	p-value
GCST000618_26	Response to antipsychotic treatment	2.000000e-07
GCST000635_26	Response to statin therapy	2.000000e-08
GCST001585_36	Breast size	8.000000e-07
GCST001915_33	Alzheimer’s disease (cognitive decline)	2.000000e-08
GCST002805_2	Body mass index	9.000000e-07
GCST003854_23	Gut microbiota (functional units)	4.000000e-08
GCST004068_36	Venous thromboembolism adjusted for sickle cell variant rs77121243-T	5.000000e-06
GCST006190_65	Diastolic blood pressure x smoking status (ever vs never) interaction (2df test)	9.000000e-10
GCST009391_416	Metabolite levels	7.000000e-06
GCST010396_152	Gut microbiota (bacterial taxa, hurdle binary method)	2.000000e-06

EFO canonical traits (5, from GWAS)

EFO ID	Trait name
EFO:0005937	longitudinal BMI measurement
EFO:0007874	gut microbiome measurement
EFO:0006336	diastolic blood pressure
EFO:0006527	smoking status measurement
EFO:0010387	phosphatidylcholine 38:5 measurement

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

PharmGKB variants

1 variants.

Variant	Genes	Level	Score	#Clin annots	Drugs
rs8014194	CLMN		0.00	0

CTD chemical–gene interactions

69 total (human), top 30 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
bisphenol A	decreases expression, affects expression, decreases methylation, increases expression, affects cotreatment	5
sodium arsenite	decreases expression, increases expression	5
Benzo(a)pyrene	decreases methylation, increases expression, affects methylation, decreases expression	5
Estradiol	decreases expression, increases reaction, affects cotreatment, increases expression	5
Valproic Acid	decreases methylation, increases expression, affects expression	4
bisphenol S	increases expression, affects cotreatment, decreases expression	3
Air Pollutants	increases abundance, increases expression, decreases expression	3
Calcitriol	affects cotreatment, increases expression, increases reaction	3
Smoke	increases abundance, increases expression, decreases expression	3
Tobacco Smoke Pollution	decreases expression, affects expression	3
Tretinoin	decreases reaction, increases expression, decreases expression	3
trichostatin A	increases expression, affects expression	2
potassium chromate(VI)	affects cotreatment, decreases expression	2
Fulvestrant	affects cotreatment, increases methylation, increases expression	2
Acetaminophen	decreases expression	2
Dexamethasone	increases expression, affects cotreatment, decreases expression	2
Nickel	decreases expression	2
Phenylmercuric Acetate	affects cotreatment, decreases expression	2
Cyclosporine	decreases expression	2
Aflatoxin B1	affects expression, increases methylation	2
Particulate Matter	decreases expression, increases abundance, increases expression	2
aristolochic acid I	decreases expression	1
FR900359	increases phosphorylation	1
bisphenol F	affects cotreatment, increases methylation	1
bufotalin	decreases expression	1
methylmercuric chloride	decreases expression	1
2,5,2’,5’-tetrachlorobiphenyl	decreases expression	1
tris(2-butoxyethyl) phosphate	decreases expression	1
mono-(2-ethylhexyl)phthalate	increases expression	1
tris(1,3-dichloro-2-propyl)phosphate	decreases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.