CLOCK-AS1

Summary

CLOCK-AS1 (CLOCK antisense RNA 1, HGNC:58790) is a long non-coding RNA gene on chromosome 4q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58790
Approved symbol	CLOCK-AS1
Name	CLOCK antisense RNA 1
Location	4q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272969
Ensembl biotype	lncRNA
Entrez	124900704

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000609234, ENST00000726601, ENST00000726602, ENST00000726603, ENST00000726604

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000609234 — 1 exons

Exon	Start	End
ENSE00003711162	55547112	55547889

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 88.31.

Top tissues by expression

122 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.31	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.48	silver quality
cortical plate	UBERON:0005343	64.01	gold quality
ventricular zone	UBERON:0003053	62.87	gold quality
bone marrow cell	CL:0002092	61.54	silver quality
ganglionic eminence	UBERON:0004023	61.41	gold quality
right testis	UBERON:0004534	59.94	gold quality
left testis	UBERON:0004533	58.41	gold quality
stromal cell of endometrium	CL:0002255	58.35	gold quality
testis	UBERON:0000473	58.01	gold quality
granulocyte	CL:0000094	55.85	gold quality
islet of Langerhans	UBERON:0000006	55.30	gold quality
prefrontal cortex	UBERON:0000451	55.29	gold quality
bone marrow	UBERON:0002371	55.21	silver quality
monocyte	CL:0000576	55.12	silver quality
pituitary gland	UBERON:0000007	55.02	gold quality
skeletal muscle tissue	UBERON:0001134	54.73	gold quality
adenohypophysis	UBERON:0002196	53.40	gold quality
calcaneal tendon	UBERON:0003701	53.11	gold quality
left adrenal gland cortex	UBERON:0035825	53.05	gold quality
gall bladder	UBERON:0002110	52.71	gold quality
right lobe of thyroid gland	UBERON:0001119	52.59	gold quality
duodenum	UBERON:0002114	52.23	gold quality
thyroid gland	UBERON:0002046	52.19	gold quality
lymph node	UBERON:0000029	52.16	gold quality
left lobe of thyroid gland	UBERON:0001120	52.16	gold quality
mucosa of stomach	UBERON:0001199	51.56	gold quality
endometrium	UBERON:0001295	51.43	gold quality
left adrenal gland	UBERON:0001234	51.25	gold quality
left coronary artery	UBERON:0001626	51.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.