CNTFR-AS1

Summary

CNTFR-AS1 (CNTFR antisense RNA 1, HGNC:48712) is a long non-coding RNA gene on chromosome 9p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48712
Approved symbol	CNTFR-AS1
Name	CNTFR antisense RNA 1
Location	9p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237159
Ensembl biotype	lncRNA
Entrez	415056
RNAcentral	URS000075A991 — lncRNA, 900 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000436360, ENST00000438244, ENST00000453642, ENST00000454187, ENST00000656721, ENST00000657464, ENST00000662777, ENST00000666375, ENST00000668876, ENST00000668957, ENST00000670893

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000436360 — 5 exons

Exon	Start	End
ENSE00001623424	34582335	34582649
ENSE00001649680	34568015	34568157
ENSE00001669696	34571348	34571444
ENSE00001670820	34569512	34569746
ENSE00001727146	34580100	34580201

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 93.54.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0653 / max 58.6410, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
96516	0.0653	3

Top tissues by expression

229 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	93.54	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.88	gold quality
right testis	UBERON:0004534	88.66	gold quality
left testis	UBERON:0004533	88.30	gold quality
testis	UBERON:0000473	85.56	gold quality
gastrocnemius	UBERON:0001388	79.35	gold quality
bone marrow cell	CL:0002092	78.67	gold quality
muscle of leg	UBERON:0001383	78.64	gold quality
buccal mucosa cell	CL:0002336	78.16	gold quality
right hemisphere of cerebellum	UBERON:0014890	75.16	gold quality
secondary oocyte	CL:0000655	74.64	silver quality
cerebellar hemisphere	UBERON:0002245	74.61	gold quality
cerebellar cortex	UBERON:0002129	74.49	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.05	gold quality
cerebellum	UBERON:0002037	73.95	gold quality
cardiac muscle of right atrium	UBERON:0003379	71.58	gold quality
left ventricle myocardium	UBERON:0006566	71.36	gold quality
tendon of biceps brachii	UBERON:0008188	70.86	gold quality
ventricular zone	UBERON:0003053	69.91	gold quality
kidney epithelium	UBERON:0004819	69.02	gold quality
vastus lateralis	UBERON:0001379	68.42	gold quality
subcutaneous adipose tissue	UBERON:0002190	68.41	gold quality
quadriceps femoris	UBERON:0001377	68.27	gold quality
ganglionic eminence	UBERON:0004023	67.75	gold quality
omental fat pad	UBERON:0010414	67.69	gold quality
peritoneum	UBERON:0002358	67.66	gold quality
sural nerve	UBERON:0015488	67.56	silver quality
adipose tissue of abdominal region	UBERON:0007808	66.95	gold quality
vena cava	UBERON:0004087	65.79	silver quality
skeletal muscle tissue	UBERON:0001134	65.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.14

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Transcription factor TP63 mediates LncRNA CNTFR-AS1 to promote DNA damage induced by neodymium oxide nanoparticles via homologous recombination repair. (PMID:37451587)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.