COA6-AS1

Summary

COA6-AS1 (COA6 antisense RNA 1, HGNC:40825) is a long non-coding RNA gene on chromosome 1q42.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40825
Approved symbol	COA6-AS1
Name	COA6 antisense RNA 1
Location	1q42.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231663
Ensembl biotype	lncRNA
Entrez	101927765
RNAcentral	URS00007E347D — lncRNA, 592 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000451795, ENST00000685022, ENST00000719173, ENST00000719174, ENST00000719175

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000451795 — 2 exons

Exon	Start	End
ENSE00003981074	234372807	234373210
ENSE00004036621	234373423	234373689

Expression profiles

Bgee: expression breadth ubiquitous, 135 present calls, max score 94.31.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 6.5505 / max 99.0274, expressed in 1674 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
18030	5.0911	1487
18031	1.4593	863

Top tissues by expression

137 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
quadriceps femoris	UBERON:0001377	94.31	silver quality
cerebellar vermis	UBERON:0004720	94.23	gold quality
putamen	UBERON:0001874	86.70	gold quality
caudate nucleus	UBERON:0001873	86.66	gold quality
nucleus accumbens	UBERON:0001882	86.32	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	83.99	gold quality
cerebellar hemisphere	UBERON:0002245	83.06	gold quality
cerebellar cortex	UBERON:0002129	82.96	gold quality
cerebellum	UBERON:0002037	82.75	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.38	silver quality
right hemisphere of cerebellum	UBERON:0014890	82.33	gold quality
muscle of leg	UBERON:0001383	82.06	gold quality
gastrocnemius	UBERON:0001388	81.62	gold quality
pituitary gland	UBERON:0000007	81.22	gold quality
right uterine tube	UBERON:0001302	81.17	gold quality
calcaneal tendon	UBERON:0003701	81.13	gold quality
adenohypophysis	UBERON:0002196	80.82	gold quality
left lobe of thyroid gland	UBERON:0001120	80.71	gold quality
brain	UBERON:0000955	80.53	gold quality
Brodmann (1909) area 9	UBERON:0013540	80.50	gold quality
thyroid gland	UBERON:0002046	80.42	gold quality
hindlimb stylopod muscle	UBERON:0004252	80.38	gold quality
apex of heart	UBERON:0002098	80.24	gold quality
right lobe of thyroid gland	UBERON:0001119	79.82	gold quality
metanephros cortex	UBERON:0010533	79.69	gold quality
monocyte	CL:0000576	79.68	gold quality
mucosa of stomach	UBERON:0001199	79.56	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	79.47	gold quality
amygdala	UBERON:0001876	79.35	gold quality
temporal lobe	UBERON:0001871	79.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.