COCH-AS1

Summary

COCH-AS1 (COCH antisense RNA 1, HGNC:58454) is a long non-coding RNA gene on chromosome 14q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58454
Approved symbol	COCH-AS1
Name	COCH antisense RNA 1
Location	14q12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000258525
Ensembl biotype	lncRNA
Entrez	100506071

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000468444, ENST00000555108, ENST00000555421, ENST00000556786, ENST00000661204

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000468444 — 3 exons

Exon	Start	End
ENSE00001845688	30885465	30886326
ENSE00002434130	30889120	30889255
ENSE00002532874	30889384	30889698

Expression profiles

Bgee: expression breadth ubiquitous, 152 present calls, max score 85.75.

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	85.75	gold quality
sperm	CL:0000019	80.97	gold quality
nucleus accumbens	UBERON:0001882	76.49	gold quality
caudate nucleus	UBERON:0001873	73.40	gold quality
body of pancreas	UBERON:0001150	73.29	gold quality
left testis	UBERON:0004533	72.55	gold quality
putamen	UBERON:0001874	72.09	gold quality
ventricular zone	UBERON:0003053	71.61	gold quality
colonic epithelium	UBERON:0000397	71.59	silver quality
cortical plate	UBERON:0005343	70.25	gold quality
testis	UBERON:0000473	70.13	gold quality
right testis	UBERON:0004534	70.12	gold quality
calcaneal tendon	UBERON:0003701	69.91	gold quality
pancreas	UBERON:0001264	67.30	gold quality
ganglionic eminence	UBERON:0004023	66.62	gold quality
adrenal tissue	UBERON:0018303	63.70	gold quality
bone marrow cell	CL:0002092	63.53	silver quality
hindlimb stylopod muscle	UBERON:0004252	63.12	gold quality
prostate gland	UBERON:0002367	62.43	gold quality
vagina	UBERON:0000996	62.00	gold quality
ectocervix	UBERON:0012249	61.53	gold quality
lymph node	UBERON:0000029	61.14	gold quality
skin of abdomen	UBERON:0001416	60.65	gold quality
vermiform appendix	UBERON:0001154	59.89	gold quality
leukocyte	CL:0000738	59.80	gold quality
monocyte	CL:0000576	59.23	gold quality
tendon	UBERON:0000043	58.70	gold quality
adenohypophysis	UBERON:0002196	57.18	gold quality
pituitary gland	UBERON:0000007	56.36	gold quality
islet of Langerhans	UBERON:0000006	55.95	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.