COL18A1-AS2

Summary

COL18A1-AS2 (COL18A1 antisense RNA 2, HGNC:40155) is a long non-coding RNA gene on chromosome 21q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40155
Approved symbol	COL18A1-AS2
Name	COL18A1 antisense RNA 2
Location	21q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224574
Ensembl biotype	lncRNA
Entrez	100874236
RNAcentral	URS00006018B2 — lncRNA, 552 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000446475

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000446475 — 4 exons

Exon	Start	End
ENSE00001601201	45408457	45408563
ENSE00001625134	45408008	45408099
ENSE00001741164	45409948	45410065
ENSE00001764084	45407386	45407620

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 74.95.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	74.95	gold quality
colonic epithelium	UBERON:0000397	66.52	gold quality
right lobe of liver	UBERON:0001114	61.88	gold quality
tonsil	UBERON:0002372	61.80	silver quality
liver	UBERON:0002107	61.58	gold quality
skeletal muscle tissue	UBERON:0001134	60.14	gold quality
adrenal tissue	UBERON:0018303	59.63	gold quality
gall bladder	UBERON:0002110	59.10	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	59.04	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.25	gold quality
prefrontal cortex	UBERON:0000451	57.42	gold quality
tibial artery	UBERON:0007610	56.35	gold quality
popliteal artery	UBERON:0002250	56.30	gold quality
kidney	UBERON:0002113	55.97	gold quality
urinary bladder	UBERON:0001255	55.31	silver quality
ovary	UBERON:0000992	54.45	gold quality
bone marrow	UBERON:0002371	54.43	gold quality
left ovary	UBERON:0002119	54.34	gold quality
corpus callosum	UBERON:0002336	54.28	gold quality
cortex of kidney	UBERON:0001225	54.26	gold quality
monocyte	CL:0000576	54.15	gold quality
frontal cortex	UBERON:0001870	53.06	gold quality
calcaneal tendon	UBERON:0003701	52.90	silver quality
uterine cervix	UBERON:0000002	52.47	gold quality
adult mammalian kidney	UBERON:0000082	51.76	gold quality
pancreas	UBERON:0001264	51.41	gold quality
body of pancreas	UBERON:0001150	51.16	gold quality
blood	UBERON:0000178	50.94	gold quality
Ammon’s horn	UBERON:0001954	50.81	gold quality
cerebral cortex	UBERON:0000956	50.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.