COL25A1-DT

Summary

COL25A1-DT (COL25A1 divergent transcript, HGNC:32963) is a long non-coding RNA gene on chromosome 4q25.

Predicted to enable nucleic acid binding activity and zinc ion binding activity.

Source: NCBI Gene 645078 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32963
Approved symbol	COL25A1-DT
Name	COL25A1 divergent transcript
Location	4q25
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ45231
Ensembl gene	ENSG00000246774
Ensembl biotype	lncRNA
Entrez	645078
RNAcentral	URS00001F2632 — lncRNA, 1951 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000500526

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000500526 — 3 exons

Exon	Start	End
ENSE00001962282	109314577	109316135
ENSE00001989698	109303035	109303327
ENSE00001990415	109313343	109313441

Expression profiles

Bgee: expression breadth broad, 56 present calls, max score 67.96.

Top tissues by expression

56 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	67.96	silver quality
ventricular zone	UBERON:0003053	58.97	silver quality
sural nerve	UBERON:0015488	57.43	silver quality
ganglionic eminence	UBERON:0004023	56.05	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	55.54	silver quality
monocyte	CL:0000576	50.97	silver quality
blood	UBERON:0000178	49.55	silver quality
saliva-secreting gland	UBERON:0001044	48.86	silver quality
prefrontal cortex	UBERON:0000451	47.90	silver quality
lymph node	UBERON:0000029	47.88	silver quality
myometrium	UBERON:0001296	46.54	silver quality
endometrium	UBERON:0001295	45.94	gold quality
gastrocnemius	UBERON:0001388	45.37	silver quality
frontal cortex	UBERON:0001870	44.87	silver quality
tibial artery	UBERON:0007610	44.70	silver quality
superior frontal gyrus	UBERON:0002661	44.63	silver quality
heart left ventricle	UBERON:0002084	43.36	silver quality
prostate gland	UBERON:0002367	42.90	silver quality
left ovary	UBERON:0002119	41.60	silver quality
right hemisphere of cerebellum	UBERON:0014890	41.60	silver quality
Brodmann (1909) area 9	UBERON:0013540	41.44	silver quality
Ammon’s horn	UBERON:0001954	41.26	silver quality
muscle layer of sigmoid colon	UBERON:0035805	41.05	silver quality
cerebellar hemisphere	UBERON:0002245	40.88	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	40.70	silver quality
caudate nucleus	UBERON:0001873	40.48	silver quality
nucleus accumbens	UBERON:0001882	40.24	silver quality
right frontal lobe	UBERON:0002810	40.09	silver quality
tibial nerve	UBERON:0001323	40.02	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	39.89	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.