COL4A2-AS1
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Summary
COL4A2-AS1 (COL4A2 antisense RNA 1, HGNC:40156) is a long non-coding RNA gene on chromosome 13q34.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:40156 |
| Approved symbol | COL4A2-AS1 |
| Name | COL4A2 antisense RNA 1 |
| Location | 13q34 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000232814 |
| Ensembl biotype | lncRNA |
| Entrez | 100874203 |
| RNAcentral | URS000075C989 — lncRNA, 539 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 lncRNA
ENST00000417970
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000417970 — 3 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001631341 | 110507647 | 110507751 |
| ENSE00001734190 | 110502575 | 110502928 |
| ENSE00001746793 | 110508099 | 110508179 |
Expression profiles
Bgee: expression breadth ubiquitous, 123 present calls, max score 83.79.
Top tissues by expression
123 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 83.79 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 81.25 | silver quality |
| left coronary artery | UBERON:0001626 | 73.75 | gold quality |
| tibial artery | UBERON:0007610 | 73.57 | gold quality |
| popliteal artery | UBERON:0002250 | 73.56 | gold quality |
| ascending aorta | UBERON:0001496 | 73.18 | gold quality |
| thoracic aorta | UBERON:0001515 | 73.12 | gold quality |
| descending thoracic aorta | UBERON:0002345 | 72.71 | gold quality |
| subcutaneous adipose tissue | UBERON:0002190 | 71.43 | gold quality |
| adipose tissue | UBERON:0001013 | 71.28 | gold quality |
| omental fat pad | UBERON:0010414 | 71.15 | gold quality |
| sural nerve | UBERON:0015488 | 70.78 | gold quality |
| left uterine tube | UBERON:0001303 | 70.69 | gold quality |
| right coronary artery | UBERON:0001625 | 70.59 | gold quality |
| muscle layer of sigmoid colon | UBERON:0035805 | 70.48 | gold quality |
| mucosa of stomach | UBERON:0001199 | 69.93 | gold quality |
| lower esophagus muscularis layer | UBERON:0035833 | 69.72 | gold quality |
| lower esophagus | UBERON:0013473 | 69.68 | gold quality |
| cortical plate | UBERON:0005343 | 69.40 | gold quality |
| stromal cell of endometrium | CL:0002255 | 68.58 | gold quality |
| myometrium | UBERON:0001296 | 68.53 | gold quality |
| esophagogastric junction muscularis propria | UBERON:0035841 | 68.28 | gold quality |
| body of uterus | UBERON:0009853 | 68.26 | gold quality |
| upper lobe of left lung | UBERON:0008952 | 67.87 | gold quality |
| tibial nerve | UBERON:0001323 | 67.78 | gold quality |
| endometrium | UBERON:0001295 | 67.31 | gold quality |
| urinary bladder | UBERON:0001255 | 67.26 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 66.89 | gold quality |
| ganglionic eminence | UBERON:0004023 | 65.28 | gold quality |
| lung | UBERON:0002048 | 65.15 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 1.29 |
Regulation
Is transcription factor: no
Literature-anchored findings (GeneRIF, showing 1)
- Long non-coding RNA COL4A2-AS1 facilitates cell proliferation and glycolysis of colorectal cancer cells via miR-20b-5p/hypoxia inducible factor 1 alpha subunit axis. (PMID:34477476)
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): brain small vessel disease 2A, autosomal dominant