COL4A2-AS2
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Summary
COL4A2-AS2 (COL4A2 antisense RNA 2, HGNC:39849) is a long non-coding RNA gene on chromosome 13q34.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:39849 |
| Approved symbol | COL4A2-AS2 |
| Name | COL4A2 antisense RNA 2 |
| Location | 13q34 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000224821 |
| Ensembl biotype | lncRNA |
| Entrez | 100129836 |
| RNAcentral | URS0002123245 — lncRNA, 1521 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 lncRNA
ENST00000458403
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000458403 — 5 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001597723 | 110457525 | 110457587 |
| ENSE00001618741 | 110458091 | 110458286 |
| ENSE00001667591 | 110456396 | 110457356 |
| ENSE00001679413 | 110457683 | 110457719 |
| ENSE00003584950 | 110463023 | 110463287 |
Expression profiles
Bgee: expression breadth broad, 97 present calls, max score 65.47.
FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2805 / max 25.0981, expressed in 78 samples.
FANTOM5 promoters (1 alternative TSS)
| Promoter ID | TPM avg | Samples expressed |
|---|---|---|
| 138247 | 0.2805 | 78 |
Top tissues by expression
97 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| sural nerve | UBERON:0015488 | 65.47 | gold quality |
| skeletal muscle tissue | UBERON:0001134 | 59.36 | silver quality |
| subcutaneous adipose tissue | UBERON:0002190 | 58.67 | gold quality |
| cortical plate | UBERON:0005343 | 57.10 | silver quality |
| adipose tissue | UBERON:0001013 | 56.01 | gold quality |
| urinary bladder | UBERON:0001255 | 55.44 | gold quality |
| popliteal artery | UBERON:0002250 | 53.97 | gold quality |
| tibial artery | UBERON:0007610 | 53.94 | gold quality |
| stromal cell of endometrium | CL:0002255 | 53.45 | silver quality |
| omental fat pad | UBERON:0010414 | 52.71 | gold quality |
| ascending aorta | UBERON:0001496 | 52.08 | gold quality |
| thoracic aorta | UBERON:0001515 | 51.39 | gold quality |
| thoracic mammary gland | UBERON:0005200 | 50.73 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 50.66 | silver quality |
| upper lobe of left lung | UBERON:0008952 | 50.39 | gold quality |
| left coronary artery | UBERON:0001626 | 50.37 | gold quality |
| lung | UBERON:0002048 | 50.33 | gold quality |
| tibial nerve | UBERON:0001323 | 50.03 | gold quality |
| blood | UBERON:0000178 | 49.59 | silver quality |
| muscle layer of sigmoid colon | UBERON:0035805 | 49.40 | gold quality |
| endometrium | UBERON:0001295 | 49.19 | silver quality |
| heart | UBERON:0000948 | 49.07 | gold quality |
| multicellular organism | UBERON:0000468 | 49.01 | gold quality |
| right atrium auricular region | UBERON:0006631 | 49.01 | gold quality |
| heart left ventricle | UBERON:0002084 | 48.72 | gold quality |
| muscle of leg | UBERON:0001383 | 48.69 | silver quality |
| esophagogastric junction muscularis propria | UBERON:0035841 | 48.60 | gold quality |
| gastrocnemius | UBERON:0001388 | 48.34 | silver quality |
| apex of heart | UBERON:0002098 | 48.21 | gold quality |
| right ovary | UBERON:0002118 | 47.95 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 0.95 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): brain small vessel disease 2A, autosomal dominant