COMMD8-DT

Summary

COMMD8-DT (COMMD8 divergent transcript, HGNC:58765) is a long non-coding RNA gene on chromosome 4p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58765
Approved symbol	COMMD8-DT
Name	COMMD8 divergent transcript
Location	4p12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000282904
Ensembl biotype	lncRNA
Entrez	143528983, 107986277

Gene structure

Transcript identifiers

Ensembl transcripts: 15 — 15 lncRNA

ENST00000634405, ENST00000634784, ENST00000635489, ENST00000797568, ENST00000797569, ENST00000797570, ENST00000797571, ENST00000797572, ENST00000797573, ENST00000797574, ENST00000797575, ENST00000797576, ENST00000797577, ENST00000797578, ENST00000797579

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000634405 — 4 exons

Exon	Start	End
ENSE00003785061	47467489	47467623
ENSE00004184385	47463153	47463246
ENSE00004184393	47470073	47470477
ENSE00004184405	47469141	47469328

Expression profiles

Bgee: expression breadth broad, 97 present calls, max score 86.86.

Top tissues by expression

208 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.86	gold quality
sperm	CL:0000019	86.34	gold quality
left testis	UBERON:0004533	80.25	gold quality
right testis	UBERON:0004534	79.99	gold quality
testis	UBERON:0000473	78.01	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.28	gold quality
ganglionic eminence	UBERON:0004023	71.39	gold quality
colonic epithelium	UBERON:0000397	69.98	silver quality
adult organism	UBERON:0007023	60.98	gold quality
ileal mucosa	UBERON:0000331	57.93	silver quality
monocyte	CL:0000576	57.88	gold quality
leukocyte	CL:0000738	57.41	gold quality
tibialis anterior	UBERON:0001385	56.56	silver quality
pancreatic ductal cell	CL:0002079	56.11	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	55.78	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
epithelial cell of pancreas	CL:0000083	54.18	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
deltoid	UBERON:0001476	53.53	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
prefrontal cortex	UBERON:0000451	53.04	gold quality
bronchial epithelial cell	CL:0002328	52.79	silver quality
bronchus	UBERON:0002185	52.21	silver quality
islet of Langerhans	UBERON:0000006	50.40	gold quality
myocardium	UBERON:0002349	50.25	gold quality
gastrocnemius	UBERON:0001388	48.86	gold quality
pancreas	UBERON:0001264	48.14	gold quality
nasal cavity mucosa	UBERON:0001826	47.57	gold quality
nasal cavity epithelium	UBERON:0005384	47.03	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.46

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.