COP1-DT

Summary

COP1-DT (COP1 divergent transcript, HGNC:55666) is a long non-coding RNA gene on chromosome 1q25.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55666
Approved symbol	COP1-DT
Name	COP1 divergent transcript
Location	1q25.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236021
Ensembl biotype	lncRNA
Entrez	121832809
RNAcentral	URS00026A2173 — lncRNA, 1742 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000456125, ENST00000654248, ENST00000660913, ENST00000691174, ENST00000691278, ENST00000701212, ENST00000832865, ENST00000832866, ENST00000832867, ENST00000832868, ENST00000832869, ENST00000832870, ENST00000832871, ENST00000832872, ENST00000832873, ENST00000832874, ENST00000832875

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456125 — 4 exons

Exon	Start	End
ENSE00001592302	176218534	176218646
ENSE00003862884	176229089	176229364
ENSE00004248785	176207625	176207871
ENSE00004248788	176230986	176231120

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 79.38.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.38	gold quality
sural nerve	UBERON:0015488	75.48	gold quality
corpus callosum	UBERON:0002336	70.53	gold quality
colonic epithelium	UBERON:0000397	70.33	silver quality
calcaneal tendon	UBERON:0003701	67.19	gold quality
bone marrow cell	CL:0002092	67.18	silver quality
islet of Langerhans	UBERON:0000006	64.92	gold quality
blood	UBERON:0000178	63.64	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.12	gold quality
granulocyte	CL:0000094	62.83	gold quality
tonsil	UBERON:0002372	61.69	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.60	gold quality
prefrontal cortex	UBERON:0000451	61.44	gold quality
bone marrow	UBERON:0002371	61.43	gold quality
lymph node	UBERON:0000029	60.78	gold quality
substantia nigra	UBERON:0002038	60.74	gold quality
endometrium	UBERON:0001295	60.54	gold quality
ganglionic eminence	UBERON:0004023	60.13	gold quality
apex of heart	UBERON:0002098	59.71	gold quality
frontal cortex	UBERON:0001870	59.63	gold quality
cortical plate	UBERON:0005343	59.63	gold quality
vermiform appendix	UBERON:0001154	59.62	gold quality
leukocyte	CL:0000738	59.58	gold quality
monocyte	CL:0000576	59.38	gold quality
mucosa of transverse colon	UBERON:0004991	59.35	gold quality
stromal cell of endometrium	CL:0002255	59.08	gold quality
Ammon’s horn	UBERON:0001954	58.99	gold quality
superior frontal gyrus	UBERON:0002661	58.98	gold quality
ventricular zone	UBERON:0003053	58.88	silver quality
cerebral cortex	UBERON:0000956	58.44	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.57

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.