COPB2-DT
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Also known as RP11-319G6.1
Summary
COPB2-DT (COPB2 divergent transcript, HGNC:55579) is a long non-coding RNA gene on chromosome 3q23.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:55579 |
| Approved symbol | COPB2-DT |
| Name | COPB2 divergent transcript |
| Location | 3q23 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Aliases | RP11-319G6.1 |
| Ensembl gene | ENSG00000248932 |
| Ensembl biotype | lncRNA |
| Entrez | 100507291 |
| RNAcentral | URS000075DDCF — lncRNA, 604 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 31 — 31 lncRNA
ENST00000381790, ENST00000504670, ENST00000507362, ENST00000510068, ENST00000512622, ENST00000514729, ENST00000515247, ENST00000653359, ENST00000655667, ENST00000658348, ENST00000659546, ENST00000660194, ENST00000661884, ENST00000662234, ENST00000664086, ENST00000664165, ENST00000670558, ENST00000685603, ENST00000686351, ENST00000690901, ENST00000691594, ENST00000731085, ENST00000731086, ENST00000731087, ENST00000731088, ENST00000731089, ENST00000731090, ENST00000731091, ENST00000731092, ENST00000731093, ENST00000731094
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000381790 — 3 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002050254 | 139539916 | 139540224 |
| ENSE00002066137 | 139583129 | 139583254 |
| ENSE00002086253 | 139577792 | 139577850 |
Expression profiles
Bgee: expression breadth ubiquitous, 172 present calls, max score 95.23.
Top tissues by expression
253 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| sperm | CL:0000019 | 95.23 | gold quality |
| left testis | UBERON:0004533 | 87.46 | gold quality |
| right testis | UBERON:0004534 | 87.40 | gold quality |
| right uterine tube | UBERON:0001302 | 87.24 | gold quality |
| primordial germ cell in gonad | CL:0000670 ∩ UBERON:0000991 | 86.28 | gold quality |
| testis | UBERON:0000473 | 85.41 | gold quality |
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 84.31 | gold quality |
| left ovary | UBERON:0002119 | 84.30 | gold quality |
| right ovary | UBERON:0002118 | 82.17 | gold quality |
| adrenal tissue | UBERON:0018303 | 81.52 | gold quality |
| cortical plate | UBERON:0005343 | 80.79 | gold quality |
| cardiac muscle of right atrium | UBERON:0003379 | 80.57 | gold quality |
| ovary | UBERON:0000992 | 80.51 | gold quality |
| left ventricle myocardium | UBERON:0006566 | 80.46 | gold quality |
| calcaneal tendon | UBERON:0003701 | 80.15 | gold quality |
| adenohypophysis | UBERON:0002196 | 79.99 | gold quality |
| sural nerve | UBERON:0015488 | 79.57 | gold quality |
| pituitary gland | UBERON:0000007 | 79.56 | gold quality |
| islet of Langerhans | UBERON:0000006 | 78.34 | gold quality |
| corpus callosum | UBERON:0002336 | 78.28 | gold quality |
| bone marrow cell | CL:0002092 | 78.06 | gold quality |
| colonic epithelium | UBERON:0000397 | 78.01 | gold quality |
| hindlimb stylopod muscle | UBERON:0004252 | 77.54 | gold quality |
| pancreas | UBERON:0001264 | 76.89 | gold quality |
| body of pancreas | UBERON:0001150 | 76.81 | gold quality |
| ventricular zone | UBERON:0003053 | 76.02 | gold quality |
| ganglionic eminence | UBERON:0004023 | 76.00 | gold quality |
| epithelial cell of pancreas | CL:0000083 | 75.95 | gold quality |
| right atrium auricular region | UBERON:0006631 | 75.18 | gold quality |
| cardiac atrium | UBERON:0002081 | 75.16 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 1.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | yes | 4.23 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): Leber congenital amaurosis