COPG2IT1

Summary

COPG2IT1 (COPG2 imprinted transcript 1, HGNC:2238) is a long non-coding RNA gene on chromosome 7q32.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:2238
Approved symbol	COPG2IT1
Name	COPG2 imprinted transcript 1
Location	7q32.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	CIT1, NCRNA00170, COPG2AS
Ensembl gene	ENSG00000286214
Ensembl biotype	lncRNA
OMIM	610581
Entrez	53844
RNAcentral	URS00007E4208 — lncRNA, 3463 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000651844

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000651844 — 1 exons

Exon	Start	End
ENSE00003850861	130538954	130546900

Expression profiles

Bgee: expression breadth ubiquitous, 221 present calls, max score 99.42.

Top tissues by expression

282 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
middle temporal gyrus	UBERON:0002771	99.42	gold quality
substantia nigra pars compacta	UBERON:0001965	99.14	gold quality
Brodmann (1909) area 23	UBERON:0013554	98.91	gold quality
pons	UBERON:0000988	98.45	gold quality
superior vestibular nucleus	UBERON:0007227	98.41	gold quality
lateral globus pallidus	UBERON:0002476	98.27	gold quality
substantia nigra pars reticulata	UBERON:0001966	98.18	gold quality
Brodmann (1909) area 10	UBERON:0013541	97.94	gold quality
orbitofrontal cortex	UBERON:0004167	97.89	gold quality
primary visual cortex	UBERON:0002436	97.23	gold quality
frontal pole	UBERON:0002795	97.22	gold quality
superior frontal gyrus	UBERON:0002661	97.17	gold quality
occipital lobe	UBERON:0002021	97.14	gold quality
lateral nuclear group of thalamus	UBERON:0002736	97.04	gold quality
Brodmann (1909) area 46	UBERON:0006483	96.80	gold quality
ventral tegmental area	UBERON:0002691	96.45	gold quality
entorhinal cortex	UBERON:0002728	96.35	gold quality
parietal lobe	UBERON:0001872	96.07	gold quality
postcentral gyrus	UBERON:0002581	95.62	gold quality
hypothalamus	UBERON:0001898	95.35	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	95.24	gold quality
medulla oblongata	UBERON:0001896	94.89	gold quality
middle frontal gyrus	UBERON:0002702	94.78	gold quality
Brodmann (1909) area 9	UBERON:0013540	94.77	gold quality
prefrontal cortex	UBERON:0000451	94.76	gold quality
dorsal motor nucleus of vagus nerve	UBERON:0002870	94.71	gold quality
frontal cortex	UBERON:0001870	94.35	gold quality
temporal lobe	UBERON:0001871	94.34	gold quality
CA1 field of hippocampus	UBERON:0003881	93.86	gold quality
cerebral cortex	UBERON:0000956	93.85	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.54

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• COPG2IT1, encoding an antisense transcript in COPG2 intron 20, is imprinted, with preferential expression from the paternal allele in fetal tissues. (PMID:10995575)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.