COPS8-DT

Summary

COPS8-DT (COPS8 divergent transcript, HGNC:55816) is a long non-coding RNA gene on chromosome 2q37.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55816
Approved symbol	COPS8-DT
Name	COPS8 divergent transcript
Location	2q37.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227252
Ensembl biotype	lncRNA
Entrez	105373951
RNAcentral	URS00026A1ABC — lncRNA, 3434 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000418430, ENST00000655155, ENST00000657607, ENST00000660650, ENST00000662924, ENST00000665401, ENST00000666653, ENST00000667175, ENST00000667956, ENST00000669095, ENST00000804432, ENST00000804433, ENST00000804434, ENST00000804435, ENST00000804436, ENST00000804437, ENST00000804438, ENST00000804439

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000418430 — 2 exons

Exon	Start	End
ENSE00001781272	237059434	237060112
ENSE00001786201	237084156	237085817

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 77.29.

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.29	gold quality
skeletal muscle tissue	UBERON:0001134	69.53	gold quality
colonic epithelium	UBERON:0000397	68.62	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.53	gold quality
stromal cell of endometrium	CL:0002255	66.31	gold quality
hindlimb stylopod muscle	UBERON:0004252	65.50	gold quality
monocyte	CL:0000576	64.42	gold quality
muscle of leg	UBERON:0001383	64.14	gold quality
leukocyte	CL:0000738	63.88	gold quality
bone marrow cell	CL:0002092	63.65	silver quality
tonsil	UBERON:0002372	63.39	gold quality
gastrocnemius	UBERON:0001388	63.30	gold quality
islet of Langerhans	UBERON:0000006	62.89	gold quality
smooth muscle tissue	UBERON:0001135	62.79	gold quality
urinary bladder	UBERON:0001255	62.79	gold quality
descending thoracic aorta	UBERON:0002345	62.29	gold quality
ventricular zone	UBERON:0003053	61.92	gold quality
calcaneal tendon	UBERON:0003701	61.46	gold quality
cortical plate	UBERON:0005343	61.46	gold quality
sural nerve	UBERON:0015488	61.44	silver quality
prefrontal cortex	UBERON:0000451	61.43	gold quality
lymph node	UBERON:0000029	61.14	gold quality
placenta	UBERON:0001987	60.77	gold quality
heart left ventricle	UBERON:0002084	60.68	gold quality
popliteal artery	UBERON:0002250	60.67	gold quality
tibial artery	UBERON:0007610	60.64	gold quality
thoracic aorta	UBERON:0001515	60.17	gold quality
ganglionic eminence	UBERON:0004023	60.11	gold quality
gall bladder	UBERON:0002110	60.01	gold quality
fallopian tube	UBERON:0003889	59.94	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.89

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.