COSMOC

Summary

COSMOC (cell fate and sterol metabolism associated divergent transcript of MOCOS, HGNC:51610) is a long non-coding RNA gene on chromosome 18q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51610
Approved symbol	COSMOC
Name	cell fate and sterol metabolism associated divergent transcript of MOCOS
Location	18q12.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260552
Ensembl biotype	lncRNA
Entrez	101927809
RNAcentral	URS0000A76CE5 — lncRNA, 603 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000568654, ENST00000687261, ENST00000700820, ENST00000738210, ENST00000738211, ENST00000738212

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000568654 — 2 exons

Exon	Start	End
ENSE00004073235	36179991	36180390
ENSE00004073237	36187235	36187474

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 85.51.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 2.3905 / max 144.3576, expressed in 986 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
171688	2.0315	929
171687	0.3219	135
171686	0.0371	12

Top tissues by expression

241 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.51	gold quality
oocyte	CL:0000023	83.47	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.87	silver quality
left ovary	UBERON:0002119	81.08	gold quality
right adrenal gland cortex	UBERON:0035827	79.82	gold quality
right adrenal gland	UBERON:0001233	79.60	gold quality
mucosa of transverse colon	UBERON:0004991	78.97	gold quality
left adrenal gland cortex	UBERON:0035825	78.88	gold quality
right lobe of liver	UBERON:0001114	78.68	gold quality
left adrenal gland	UBERON:0001234	78.66	gold quality
right ovary	UBERON:0002118	77.84	gold quality
ovary	UBERON:0000992	76.90	gold quality
adrenal gland	UBERON:0002369	76.48	gold quality
adrenal cortex	UBERON:0001235	76.38	gold quality
gall bladder	UBERON:0002110	75.09	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	74.00	gold quality
descending thoracic aorta	UBERON:0002345	73.83	gold quality
oviduct epithelium	UBERON:0004804	73.70	gold quality
thoracic aorta	UBERON:0001515	72.89	gold quality
ascending aorta	UBERON:0001496	72.86	gold quality
right coronary artery	UBERON:0001625	72.31	gold quality
duodenum	UBERON:0002114	71.33	gold quality
adrenal tissue	UBERON:0018303	70.73	gold quality
left coronary artery	UBERON:0001626	70.31	gold quality
fallopian tube	UBERON:0003889	69.66	gold quality
transverse colon	UBERON:0001157	69.62	gold quality
aorta	UBERON:0000947	69.35	gold quality
cortical plate	UBERON:0005343	69.22	gold quality
liver	UBERON:0002107	68.98	gold quality
small intestine	UBERON:0002108	68.98	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.82

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.