COTL1-AS1

Summary

COTL1-AS1 (COTL1 antisense RNA 1, HGNC:58542) is a long non-coding RNA gene on chromosome 16q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58542
Approved symbol	COTL1-AS1
Name	COTL1 antisense RNA 1
Location	16q24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261471
Ensembl biotype	lncRNA
Entrez	142592837

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000564809, ENST00000747022

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000564809 — 1 exons

Exon	Start	End
ENSE00002576586	84594393	84596826

Expression profiles

Bgee: expression breadth broad, 89 present calls, max score 76.00.

Top tissues by expression

89 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	76.00	gold quality
bone marrow cell	CL:0002092	70.07	silver quality
sural nerve	UBERON:0015488	66.62	silver quality
bone marrow	UBERON:0002371	63.52	gold quality
tonsil	UBERON:0002372	62.93	gold quality
colonic epithelium	UBERON:0000397	62.29	silver quality
monocyte	CL:0000576	61.34	gold quality
lymph node	UBERON:0000029	60.97	gold quality
spleen	UBERON:0002106	60.85	gold quality
vermiform appendix	UBERON:0001154	60.73	gold quality
leukocyte	CL:0000738	60.71	gold quality
skeletal muscle tissue	UBERON:0001134	60.33	silver quality
duodenum	UBERON:0002114	59.09	gold quality
urinary bladder	UBERON:0001255	57.48	gold quality
multicellular organism	UBERON:0000468	55.71	gold quality
small intestine	UBERON:0002108	55.58	gold quality
small intestine Peyer’s patch	UBERON:0003454	55.31	gold quality
granulocyte	CL:0000094	52.95	gold quality
calcaneal tendon	UBERON:0003701	51.70	silver quality
descending thoracic aorta	UBERON:0002345	49.37	gold quality
intestine	UBERON:0000160	49.26	gold quality
liver	UBERON:0002107	48.98	silver quality
right lung	UBERON:0002167	48.00	gold quality
pancreas	UBERON:0001264	47.28	silver quality
gastrocnemius	UBERON:0001388	47.28	silver quality
gall bladder	UBERON:0002110	47.22	gold quality
adrenal gland	UBERON:0002369	46.90	silver quality
prefrontal cortex	UBERON:0000451	46.83	silver quality
placenta	UBERON:0001987	46.41	silver quality
left uterine tube	UBERON:0001303	46.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.