CPNE8-AS1

Summary

CPNE8-AS1 (CPNE8 antisense RNA 1, HGNC:53937) is a long non-coding RNA gene on chromosome 12q12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53937
Approved symbol	CPNE8-AS1
Name	CPNE8 antisense RNA 1
Location	12q12
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-396F22.1
Ensembl gene	ENSG00000257718
Ensembl biotype	lncRNA
Entrez	107984504
RNAcentral	URS0002A5B694 — lncRNA, 1280 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000551152, ENST00000790749, ENST00000790750

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000551152 — 2 exons

Exon	Start	End
ENSE00004171297	38909310	38909593
ENSE00004171298	38905698	38906693

Expression profiles

Bgee: expression breadth ubiquitous, 157 present calls, max score 96.39.

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	96.39	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.18	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.35	gold quality
right lobe of liver	UBERON:0001114	77.30	gold quality
right testis	UBERON:0004534	75.63	gold quality
left testis	UBERON:0004533	74.91	gold quality
testis	UBERON:0000473	72.64	gold quality
islet of Langerhans	UBERON:0000006	70.16	gold quality
right atrium auricular region	UBERON:0006631	69.04	gold quality
cortical plate	UBERON:0005343	68.96	gold quality
amygdala	UBERON:0001876	68.65	gold quality
mucosa of stomach	UBERON:0001199	68.56	gold quality
cardiac atrium	UBERON:0002081	68.35	gold quality
anterior cingulate cortex	UBERON:0009835	68.01	gold quality
liver	UBERON:0002107	67.91	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	67.71	gold quality
myocardium	UBERON:0002349	67.53	gold quality
left adrenal gland	UBERON:0001234	67.44	gold quality
smooth muscle tissue	UBERON:0001135	67.32	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.15	gold quality
monocyte	CL:0000576	66.92	gold quality
left adrenal gland cortex	UBERON:0035825	66.92	gold quality
cardiac muscle of right atrium	UBERON:0003379	66.83	gold quality
kidney epithelium	UBERON:0004819	66.81	gold quality
stromal cell of endometrium	CL:0002255	66.69	gold quality
right frontal lobe	UBERON:0002810	66.63	gold quality
leukocyte	CL:0000738	66.51	gold quality
left ventricle myocardium	UBERON:0006566	66.51	gold quality
rectum	UBERON:0001052	66.08	gold quality
prefrontal cortex	UBERON:0000451	65.85	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	8.68

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.