CRIM1-DT

Summary

CRIM1-DT (CRIM1 divergent transcript, HGNC:54057) is a long non-coding RNA gene on chromosome 2p22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54057
Approved symbol	CRIM1-DT
Name	CRIM1 divergent transcript
Location	2p22.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-490M8.1
Ensembl gene	ENSG00000260025
Ensembl biotype	lncRNA
Entrez	100288911
RNAcentral	URS000075E106 — lncRNA, 733 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000565283, ENST00000822053, ENST00000822054, ENST00000822055

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000565283 — 1 exons

Exon	Start	End
ENSE00004229456	36354066	36355488

Expression profiles

Bgee: expression breadth ubiquitous, 170 present calls, max score 95.31.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.9525 / max 83.2777, expressed in 1362 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
27726	7.8559	1360
27727	0.0966	47

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
anterior cingulate cortex	UBERON:0009835	95.31	gold quality
right frontal lobe	UBERON:0002810	93.60	gold quality
Brodmann (1909) area 9	UBERON:0013540	93.58	gold quality
caudate nucleus	UBERON:0001873	93.06	gold quality
nucleus accumbens	UBERON:0001882	92.46	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	92.24	gold quality
putamen	UBERON:0001874	91.78	gold quality
amygdala	UBERON:0001876	91.63	gold quality
popliteal artery	UBERON:0002250	90.71	gold quality
tibial artery	UBERON:0007610	90.70	gold quality
prefrontal cortex	UBERON:0000451	90.49	gold quality
hypothalamus	UBERON:0001898	90.29	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.24	gold quality
right coronary artery	UBERON:0001625	89.22	gold quality
aorta	UBERON:0000947	89.15	gold quality
left coronary artery	UBERON:0001626	88.66	gold quality
neocortex	UBERON:0001950	88.14	gold quality
ascending aorta	UBERON:0001496	87.80	gold quality
thoracic aorta	UBERON:0001515	87.74	gold quality
frontal cortex	UBERON:0001870	87.41	gold quality
descending thoracic aorta	UBERON:0002345	86.51	gold quality
coronary artery	UBERON:0001621	86.41	gold quality
gastrocnemius	UBERON:0001388	86.26	gold quality
cerebral cortex	UBERON:0000956	86.19	gold quality
muscle of leg	UBERON:0001383	85.79	gold quality
omental fat pad	UBERON:0010414	85.76	gold quality
peritoneum	UBERON:0002358	85.64	gold quality
lower esophagus muscularis layer	UBERON:0035833	85.26	gold quality
lower esophagus	UBERON:0013473	85.20	gold quality
forebrain	UBERON:0001890	85.08	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.