CRK-AS1
gene geneOn this page
Also known as RP11-818O24.3
Summary
CRK-AS1 (CRK antisense RNA 1, HGNC:58106) is a long non-coding RNA gene on chromosome 17p13.3.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:58106 |
| Approved symbol | CRK-AS1 |
| Name | CRK antisense RNA 1 |
| Location | 17p13.3 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Aliases | RP11-818O24.3 |
| Ensembl gene | ENSG00000262777 |
| Ensembl biotype | lncRNA |
| Entrez | 137805487 |
| RNAcentral | URS00002C5554 — lncRNA, 570 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 2 — 2 lncRNA
ENST00000570924, ENST00000576825
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000570924 — 2 exons
| Exon | Start | End |
|---|---|---|
| ENSE00002631430 | 1424473 | 1424917 |
| ENSE00002668244 | 1426239 | 1426363 |
Expression profiles
Bgee: expression breadth ubiquitous, 129 present calls, max score 83.88.
Top tissues by expression
129 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| male germ line stem cell (sensu Vertebrata) in testis | CL:0000089 ∩ UBERON:0000473 | 83.88 | gold quality |
| skeletal muscle tissue | UBERON:0001134 | 70.46 | gold quality |
| bone marrow cell | CL:0002092 | 70.25 | silver quality |
| hindlimb stylopod muscle | UBERON:0004252 | 67.86 | gold quality |
| blood | UBERON:0000178 | 67.79 | gold quality |
| stromal cell of endometrium | CL:0002255 | 67.52 | gold quality |
| colonic epithelium | UBERON:0000397 | 67.10 | silver quality |
| ganglionic eminence | UBERON:0004023 | 66.96 | gold quality |
| monocyte | CL:0000576 | 66.66 | gold quality |
| lymph node | UBERON:0000029 | 65.59 | gold quality |
| bone marrow | UBERON:0002371 | 65.33 | gold quality |
| liver | UBERON:0002107 | 64.91 | gold quality |
| tonsil | UBERON:0002372 | 64.35 | gold quality |
| urinary bladder | UBERON:0001255 | 63.80 | gold quality |
| left uterine tube | UBERON:0001303 | 63.75 | gold quality |
| apex of heart | UBERON:0002098 | 63.72 | gold quality |
| right coronary artery | UBERON:0001625 | 63.59 | gold quality |
| spleen | UBERON:0002106 | 63.32 | gold quality |
| right lobe of liver | UBERON:0001114 | 63.30 | gold quality |
| body of stomach | UBERON:0001161 | 63.17 | gold quality |
| transverse colon | UBERON:0001157 | 63.14 | gold quality |
| small intestine | UBERON:0002108 | 62.93 | gold quality |
| metanephros cortex | UBERON:0010533 | 62.82 | gold quality |
| rectum | UBERON:0001052 | 62.77 | gold quality |
| esophagogastric junction muscularis propria | UBERON:0035841 | 62.71 | gold quality |
| right lobe of thyroid gland | UBERON:0001119 | 62.68 | gold quality |
| small intestine Peyer’s patch | UBERON:0003454 | 62.65 | gold quality |
| body of uterus | UBERON:0009853 | 62.63 | gold quality |
| stomach | UBERON:0000945 | 62.55 | gold quality |
| duodenum | UBERON:0002114 | 62.53 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 0.27 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): chromosome 17p13.3 duplication syndrome