CRPPA-AS1

Summary

CRPPA-AS1 (CRPPA antisense RNA 1, HGNC:48962) is a long non-coding RNA gene on chromosome 7p21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48962
Approved symbol	CRPPA-AS1
Name	CRPPA antisense RNA 1
Location	7p21.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229688
Ensembl biotype	lncRNA
Entrez	100506025
RNAcentral	URS00007599CA — lncRNA, 2264 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000436328, ENST00000438573, ENST00000457112, ENST00000579293, ENST00000582683, ENST00000655000, ENST00000663812, ENST00000819452, ENST00000819453, ENST00000819454

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000436328 — 2 exons

Exon	Start	End
ENSE00001623288	16269249	16269590
ENSE00001673133	16270517	16270604

Expression profiles

Bgee: expression breadth ubiquitous, 147 present calls, max score 96.39.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0155 / max 12.6304, expressed in 4 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
77317	0.0155	4

Top tissues by expression

231 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	96.39	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.74	gold quality
left testis	UBERON:0004533	78.12	gold quality
right testis	UBERON:0004534	77.24	gold quality
testis	UBERON:0000473	76.35	gold quality
bone marrow cell	CL:0002092	69.31	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.02	gold quality
ventricular zone	UBERON:0003053	64.37	gold quality
ganglionic eminence	UBERON:0004023	64.21	gold quality
stromal cell of endometrium	CL:0002255	57.90	gold quality
calcaneal tendon	UBERON:0003701	57.13	gold quality
adrenal tissue	UBERON:0018303	56.60	gold quality
monocyte	CL:0000576	54.93	gold quality
endothelial cell	CL:0000115	53.64	gold quality
lower esophagus mucosa	UBERON:0035834	53.29	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.59	gold quality
prefrontal cortex	UBERON:0000451	52.35	gold quality
islet of Langerhans	UBERON:0000006	52.10	gold quality
muscle of leg	UBERON:0001383	51.96	gold quality
right ovary	UBERON:0002118	51.93	gold quality
left ovary	UBERON:0002119	51.70	gold quality
lymph node	UBERON:0000029	51.21	gold quality
right lobe of liver	UBERON:0001114	51.19	gold quality
buccal mucosa cell	CL:0002336	51.04	silver quality
gastrocnemius	UBERON:0001388	50.96	gold quality
tendon	UBERON:0000043	50.69	gold quality
smooth muscle tissue	UBERON:0001135	50.43	gold quality
stomach	UBERON:0000945	50.12	gold quality
ovary	UBERON:0000992	49.49	gold quality
gall bladder	UBERON:0002110	49.49	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.55

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.