CRTC3-AS1

Summary

CRTC3-AS1 (CRTC3 antisense RNA 1, HGNC:51433) is a long non-coding RNA gene on chromosome 15q26.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51433
Approved symbol	CRTC3-AS1
Name	CRTC3 antisense RNA 1
Location	15q26.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259736
Ensembl biotype	lncRNA
Entrez	101926895
RNAcentral	URS000075B303 — lncRNA, 654 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000558105, ENST00000559531, ENST00000764740, ENST00000764741, ENST00000764742, ENST00000764743, ENST00000764744, ENST00000764745, ENST00000764746, ENST00000764747, ENST00000764748, ENST00000764749, ENST00000764750, ENST00000764751, ENST00000764752, ENST00000764753, ENST00000764754, ENST00000764755, ENST00000764756

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000558105 — 3 exons

Exon	Start	End
ENSE00002537841	90716977	90717049
ENSE00002557785	90714921	90715042
ENSE00002567800	90712993	90713299

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 79.15.

FANTOM5 (CAGE): breadth broad, TPM avg 1.2268 / max 15.8621, expressed in 634 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
151576	1.2268	634

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.15	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	75.31	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.51	gold quality
cortical plate	UBERON:0005343	68.15	gold quality
bone marrow cell	CL:0002092	67.57	silver quality
ganglionic eminence	UBERON:0004023	66.78	gold quality
sural nerve	UBERON:0015488	66.45	silver quality
ventricular zone	UBERON:0003053	65.77	gold quality
calcaneal tendon	UBERON:0003701	63.55	gold quality
tonsil	UBERON:0002372	62.50	gold quality
islet of Langerhans	UBERON:0000006	62.03	gold quality
right lobe of liver	UBERON:0001114	61.70	gold quality
liver	UBERON:0002107	61.46	gold quality
bone marrow	UBERON:0002371	60.63	gold quality
right uterine tube	UBERON:0001302	60.46	gold quality
duodenum	UBERON:0002114	60.43	gold quality
corpus callosum	UBERON:0002336	59.53	gold quality
leukocyte	CL:0000738	59.48	gold quality
monocyte	CL:0000576	59.23	gold quality
fallopian tube	UBERON:0003889	58.38	gold quality
pancreas	UBERON:0001264	57.77	gold quality
lymph node	UBERON:0000029	57.69	gold quality
thyroid gland	UBERON:0002046	56.75	gold quality
granulocyte	CL:0000094	56.48	gold quality
cortex of kidney	UBERON:0001225	56.26	gold quality
prefrontal cortex	UBERON:0000451	56.07	gold quality
gall bladder	UBERON:0002110	56.02	gold quality
left lobe of thyroid gland	UBERON:0001120	55.99	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.97	gold quality
blood	UBERON:0000178	55.81	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.18

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.