CTTN-DT

Summary

CTTN-DT (CTTN divergent transcript, HGNC:55592) is a long non-coding RNA gene on chromosome 11q13.3.

Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting.

Source: NCBI Gene 121233926 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55592
Approved symbol	CTTN-DT
Name	CTTN divergent transcript
Location	11q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246889
Ensembl biotype	lncRNA
Entrez	121233926
RNAcentral	URS00026A2609 — lncRNA, 4782 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000500185, ENST00000524619, ENST00000530690, ENST00000792399

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000500185 — 2 exons

Exon	Start	End
ENSE00004174344	70373410	70375620
ENSE00004174347	70398098	70398492

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 78.65.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	78.65	gold quality
leukocyte	CL:0000738	77.71	gold quality
sural nerve	UBERON:0015488	75.94	gold quality
endometrium	UBERON:0001295	74.41	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.35	silver quality
left ovary	UBERON:0002119	74.11	gold quality
bone marrow cell	CL:0002092	73.14	gold quality
ovary	UBERON:0000992	73.01	gold quality
right uterine tube	UBERON:0001302	72.82	gold quality
subcutaneous adipose tissue	UBERON:0002190	72.35	gold quality
body of uterus	UBERON:0009853	72.18	gold quality
right ovary	UBERON:0002118	72.10	gold quality
cerebellar hemisphere	UBERON:0002245	71.85	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.84	gold quality
cerebellum	UBERON:0002037	71.79	gold quality
cerebellar cortex	UBERON:0002129	71.71	gold quality
ganglionic eminence	UBERON:0004023	71.70	gold quality
tibial nerve	UBERON:0001323	71.69	gold quality
pituitary gland	UBERON:0000007	71.63	gold quality
adipose tissue	UBERON:0001013	71.46	gold quality
apex of heart	UBERON:0002098	71.40	gold quality
endocervix	UBERON:0000458	71.33	gold quality
myometrium	UBERON:0001296	71.25	gold quality
skeletal muscle tissue	UBERON:0001134	71.13	gold quality
popliteal artery	UBERON:0002250	70.96	gold quality
tibial artery	UBERON:0007610	70.96	gold quality
thyroid gland	UBERON:0002046	70.85	gold quality
right coronary artery	UBERON:0001625	70.78	gold quality
blood	UBERON:0000178	70.75	gold quality
left lobe of thyroid gland	UBERON:0001120	70.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.02

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.