CXXC4-AS1

Summary

CXXC4-AS1 (CXXC4 antisense RNA 1, HGNC:41054) is a long non-coding RNA gene on chromosome 4q24.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41054
Approved symbol	CXXC4-AS1
Name	CXXC4 antisense RNA 1
Location	4q24
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245384
Ensembl biotype	lncRNA
Entrez	101929468
RNAcentral	URS0000175810 — lncRNA, 2968 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 26 — 26 lncRNA

ENST00000500179, ENST00000508358, ENST00000655215, ENST00000664466, ENST00000723209, ENST00000723210, ENST00000723211, ENST00000723212, ENST00000723213, ENST00000723214, ENST00000723215, ENST00000723216, ENST00000723217, ENST00000723218, ENST00000723219, ENST00000723506, ENST00000723507, ENST00000723508, ENST00000723509, ENST00000723510, ENST00000723511, ENST00000723512, ENST00000723513, ENST00000723514, ENST00000723515, ENST00000723516

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000500179 — 10 exons

Exon	Start	End
ENSE00001959673	104646899	104646935
ENSE00001964074	104676053	104676186
ENSE00001970424	104684501	104684599
ENSE00001979494	104643011	104643139
ENSE00001980044	104643321	104643402
ENSE00001982090	104695591	104697592
ENSE00001983395	104490965	104491060
ENSE00001989075	104661421	104661577
ENSE00001990052	104672639	104672748
ENSE00002505753	104659085	104659206

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 72.45.

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.45	silver quality
liver	UBERON:0002107	63.96	gold quality
nucleus accumbens	UBERON:0001882	63.06	gold quality
putamen	UBERON:0001874	62.12	gold quality
primary visual cortex	UBERON:0002436	62.04	gold quality
ventricular zone	UBERON:0003053	61.76	gold quality
cortical plate	UBERON:0005343	61.53	silver quality
caudate nucleus	UBERON:0001873	61.26	gold quality
superior frontal gyrus	UBERON:0002661	58.82	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.68	silver quality
Brodmann (1909) area 9	UBERON:0013540	57.78	gold quality
prefrontal cortex	UBERON:0000451	57.36	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	56.75	gold quality
frontal cortex	UBERON:0001870	56.34	gold quality
ganglionic eminence	UBERON:0004023	55.99	silver quality
cerebral cortex	UBERON:0000956	55.72	gold quality
right frontal lobe	UBERON:0002810	54.66	gold quality
brain	UBERON:0000955	54.53	gold quality
calcaneal tendon	UBERON:0003701	54.39	silver quality
anterior cingulate cortex	UBERON:0009835	54.08	gold quality
right uterine tube	UBERON:0001302	53.64	gold quality
Ammon’s horn	UBERON:0001954	53.35	gold quality
skeletal muscle tissue	UBERON:0001134	52.31	silver quality
urinary bladder	UBERON:0001255	51.98	silver quality
muscle of leg	UBERON:0001383	51.85	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	51.26	gold quality
corpus callosum	UBERON:0002336	50.45	silver quality
hypothalamus	UBERON:0001898	50.21	gold quality
monocyte	CL:0000576	49.77	silver quality
islet of Langerhans	UBERON:0000006	49.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.07

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.