CYLD-AS2

Summary

CYLD-AS2 (CYLD antisense RNA 2, HGNC:56848) is a long non-coding RNA gene on chromosome 16q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56848
Approved symbol	CYLD-AS2
Name	CYLD antisense RNA 2
Location	16q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260616
Ensembl biotype	lncRNA
Entrez	105371251
RNAcentral	URS00026A1AA1 — lncRNA, 794 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000564510, ENST00000575917, ENST00000756685

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000564510 — 3 exons

Exon	Start	End
ENSE00002578627	50803037	50803338
ENSE00002588313	50783859	50784189
ENSE00002611705	50802123	50802276

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 93.15.

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.15	gold quality
bone marrow	UBERON:0002371	71.86	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.07	gold quality
colonic epithelium	UBERON:0000397	70.58	gold quality
ganglionic eminence	UBERON:0004023	70.44	gold quality
bone marrow cell	CL:0002092	68.11	silver quality
left testis	UBERON:0004533	68.04	gold quality
testis	UBERON:0000473	67.67	gold quality
right testis	UBERON:0004534	67.19	gold quality
blood	UBERON:0000178	65.74	gold quality
skeletal muscle tissue	UBERON:0001134	61.26	silver quality
monocyte	CL:0000576	60.69	gold quality
placenta	UBERON:0001987	60.14	gold quality
right lung	UBERON:0002167	60.08	gold quality
cortex of kidney	UBERON:0001225	59.97	gold quality
duodenum	UBERON:0002114	59.43	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.43	gold quality
vermiform appendix	UBERON:0001154	58.24	gold quality
urinary bladder	UBERON:0001255	58.18	gold quality
liver	UBERON:0002107	58.05	gold quality
skin of abdomen	UBERON:0001416	57.71	gold quality
rectum	UBERON:0001052	57.69	gold quality
tonsil	UBERON:0002372	57.11	silver quality
zone of skin	UBERON:0000014	56.72	gold quality
smooth muscle tissue	UBERON:0001135	56.50	gold quality
uterine cervix	UBERON:0000002	56.43	gold quality
calcaneal tendon	UBERON:0003701	56.03	gold quality
vagina	UBERON:0000996	55.93	gold quality
skin of leg	UBERON:0001511	55.88	gold quality
lymph node	UBERON:0000029	55.85	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.58

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.