CYP3A4-AS1

Summary

CYP3A4-AS1 (CYP3A4 antisense RNA 1, HGNC:58107) is a long non-coding RNA gene on chromosome 7q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58107
Approved symbol	CYP3A4-AS1
Name	CYP3A4 antisense RNA 1
Location	7q22.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC069294.1
Ensembl gene	ENSG00000273407
Ensembl biotype	lncRNA
Entrez	137805488
RNAcentral	URS000038D554 — lncRNA, 350 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000608397

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000608397 — 1 exons

Exon	Start	End
ENSE00003706784	99766543	99766892

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 92.58.

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	92.58	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.67	gold quality
hindlimb stylopod muscle	UBERON:0004252	76.65	gold quality
liver	UBERON:0002107	75.67	gold quality
right lobe of liver	UBERON:0001114	73.00	gold quality
cerebellar hemisphere	UBERON:0002245	71.68	gold quality
cerebellar cortex	UBERON:0002129	71.23	gold quality
ventricular zone	UBERON:0003053	71.17	gold quality
cerebellum	UBERON:0002037	71.00	gold quality
duodenum	UBERON:0002114	70.84	gold quality
right hemisphere of cerebellum	UBERON:0014890	70.65	gold quality
skeletal muscle tissue	UBERON:0001134	69.94	silver quality
superior frontal gyrus	UBERON:0002661	68.42	gold quality
ganglionic eminence	UBERON:0004023	68.38	gold quality
bone marrow cell	CL:0002092	68.01	silver quality
cortical plate	UBERON:0005343	67.60	gold quality
lymph node	UBERON:0000029	65.52	gold quality
primary visual cortex	UBERON:0002436	64.95	gold quality
bone marrow	UBERON:0002371	64.65	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.40	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	63.55	gold quality
right frontal lobe	UBERON:0002810	62.37	gold quality
anterior cingulate cortex	UBERON:0009835	62.05	gold quality
brain	UBERON:0000955	61.91	gold quality
frontal cortex	UBERON:0001870	61.67	gold quality
small intestine	UBERON:0002108	61.60	gold quality
putamen	UBERON:0001874	61.56	gold quality
Ammon’s horn	UBERON:0001954	61.31	gold quality
caudate nucleus	UBERON:0001873	60.82	gold quality
monocyte	CL:0000576	60.68	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.