CYP4A22-AS1

Summary

CYP4A22-AS1 (CYP4A22 antisense RNA 1, HGNC:43715) is a long non-coding RNA gene on chromosome 1p33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43715
Approved symbol	CYP4A22-AS1
Name	CYP4A22 antisense RNA 1
Location	1p33
Locus type	RNA, long non-coding
Status	Approved
Aliases	ncRNA-a3
Ensembl gene	ENSG00000225506
Ensembl biotype	lncRNA
Entrez	105378701
RNAcentral	URS0002853A1E — lncRNA, 3995 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000444042, ENST00000702865, ENST00000815597, ENST00000815598, ENST00000815708, ENST00000815709

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000444042 — 4 exons

Exon	Start	End
ENSE00001622106	47179190	47179271
ENSE00001667533	47178171	47178449
ENSE00002447187	47177035	47177069
ENSE00002462994	47096653	47097177

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 80.12.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0142 / max 15.0808, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
12209	0.0142	3

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.12	gold quality
quadriceps femoris	UBERON:0001377	79.50	gold quality
thymus	UBERON:0002370	78.26	silver quality
sural nerve	UBERON:0015488	67.77	gold quality
bone marrow cell	CL:0002092	67.30	silver quality
colonic epithelium	UBERON:0000397	66.79	silver quality
cortical plate	UBERON:0005343	64.30	gold quality
skeletal muscle tissue	UBERON:0001134	63.66	gold quality
adult mammalian kidney	UBERON:0000082	63.55	gold quality
cerebellar vermis	UBERON:0004720	63.05	gold quality
kidney	UBERON:0002113	62.88	gold quality
ventricular zone	UBERON:0003053	61.72	gold quality
rectum	UBERON:0001052	61.34	gold quality
ganglionic eminence	UBERON:0004023	61.10	gold quality
cortex of kidney	UBERON:0001225	61.00	gold quality
superior frontal gyrus	UBERON:0002661	60.88	gold quality
duodenum	UBERON:0002114	60.77	gold quality
primary visual cortex	UBERON:0002436	59.72	gold quality
mucosa of transverse colon	UBERON:0004991	59.64	gold quality
gall bladder	UBERON:0002110	59.60	gold quality
prefrontal cortex	UBERON:0000451	59.02	gold quality
endometrium	UBERON:0001295	58.04	gold quality
bone marrow	UBERON:0002371	57.96	gold quality
islet of Langerhans	UBERON:0000006	57.86	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.57	gold quality
calcaneal tendon	UBERON:0003701	56.79	gold quality
lymph node	UBERON:0000029	56.73	gold quality
liver	UBERON:0002107	56.60	gold quality
frontal cortex	UBERON:0001870	55.87	gold quality
tonsil	UBERON:0002372	55.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.90

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.