CYP51A1-AS1

Summary

CYP51A1-AS1 (CYP51A1 antisense RNA 1, HGNC:50694) is a long non-coding RNA gene on chromosome 7q21.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50694
Approved symbol	CYP51A1-AS1
Name	CYP51A1 antisense RNA 1
Location	7q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000453068, LRRD1-AS1
Ensembl gene	ENSG00000188693
Ensembl biotype	lncRNA
Entrez	613126
RNAcentral	URS000075D847 — lncRNA, 3014 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000453068, ENST00000653494, ENST00000849815, ENST00000849816

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000453068 — 5 exons

Exon	Start	End
ENSE00001621058	92142402	92142734
ENSE00001676077	92138767	92138951
ENSE00001729140	92178851	92180725
ENSE00001741321	92134604	92135082
ENSE00001800489	92164980	92165064

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 78.08.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3414 / max 27.0833, expressed in 168 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
79517	0.3233	153
79516	0.0181	5

Top tissues by expression

224 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.08	gold quality
bone marrow cell	CL:0002092	69.58	silver quality
right testis	UBERON:0004534	68.35	gold quality
left testis	UBERON:0004533	67.75	gold quality
testis	UBERON:0000473	66.04	gold quality
sperm	CL:0000019	65.91	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	62.45	gold quality
cortical plate	UBERON:0005343	60.13	silver quality
ganglionic eminence	UBERON:0004023	59.22	gold quality
tibialis anterior	UBERON:0001385	58.19	silver quality
islet of Langerhans	UBERON:0000006	54.58	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
stromal cell of endometrium	CL:0002255	53.91	silver quality
prefrontal cortex	UBERON:0000451	53.58	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
hindlimb stylopod muscle	UBERON:0004252	53.46	gold quality
epithelial cell of pancreas	CL:0000083	53.02	gold quality
ileal mucosa	UBERON:0000331	52.41	silver quality
cerebellar cortex	UBERON:0002129	51.01	silver quality
cerebellar hemisphere	UBERON:0002245	50.96	silver quality
leukocyte	CL:0000738	50.54	silver quality
myocardium	UBERON:0002349	50.25	gold quality
cerebellum	UBERON:0002037	50.22	silver quality
right hemisphere of cerebellum	UBERON:0014890	50.02	silver quality
pancreas	UBERON:0001264	49.38	gold quality
monocyte	CL:0000576	49.12	silver quality
Brodmann (1909) area 9	UBERON:0013540	49.03	gold quality
adenohypophysis	UBERON:0002196	48.92	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.01

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.