CYYR1-AS1

Summary

CYYR1-AS1 (CYYR1 antisense RNA 1, HGNC:39560) is a long non-coding RNA gene on chromosome 21q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:39560
Approved symbol	CYYR1-AS1
Name	CYYR1 antisense RNA 1
Location	21q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000197934
Ensembl biotype	lncRNA
OMIM	616021
Entrez	100996571
RNAcentral	URS0000253C39 — lncRNA, 3412 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000357401, ENST00000414486, ENST00000421771, ENST00000429340, ENST00000444306, ENST00000452460, ENST00000717108, ENST00000717648, ENST00000723681, ENST00000723682

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000357401 — 4 exons

Exon	Start	End
ENSE00001399667	26550319	26552127
ENSE00001543348	26567957	26569252
ENSE00001543351	26405943	26406128
ENSE00004031661	26503582	26503702

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 79.21.

FANTOM5 (CAGE): breadth broad, TPM avg 0.4348 / max 31.2940, expressed in 200 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
188690	0.4348	200

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	79.21	gold quality
thymus	UBERON:0002370	75.73	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.13	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.97	gold quality
adrenal tissue	UBERON:0018303	72.87	gold quality
cerebellar vermis	UBERON:0004720	72.70	gold quality
ganglionic eminence	UBERON:0004023	67.48	gold quality
calcaneal tendon	UBERON:0003701	67.24	gold quality
quadriceps femoris	UBERON:0001377	65.24	gold quality
corpus callosum	UBERON:0002336	64.49	gold quality
cortical plate	UBERON:0005343	57.21	silver quality
skeletal muscle tissue	UBERON:0001134	54.97	silver quality
bone marrow	UBERON:0002371	54.67	gold quality
blood	UBERON:0000178	54.41	silver quality
hindlimb stylopod muscle	UBERON:0004252	53.51	silver quality
prefrontal cortex	UBERON:0000451	52.72	gold quality
muscle of leg	UBERON:0001383	52.53	gold quality
adrenal gland	UBERON:0002369	52.51	gold quality
monocyte	CL:0000576	52.32	gold quality
endometrium	UBERON:0001295	51.43	silver quality
gastrocnemius	UBERON:0001388	51.18	gold quality
islet of Langerhans	UBERON:0000006	51.00	gold quality
primary visual cortex	UBERON:0002436	50.91	gold quality
right adrenal gland cortex	UBERON:0035827	50.81	gold quality
placenta	UBERON:0001987	50.63	gold quality
right adrenal gland	UBERON:0001233	50.45	gold quality
left adrenal gland cortex	UBERON:0035825	50.26	gold quality
superior frontal gyrus	UBERON:0002661	49.90	gold quality
kidney	UBERON:0002113	49.86	gold quality
liver	UBERON:0002107	49.70	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.71

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.