DAB1-AS1

Summary

DAB1-AS1 (DAB1 antisense RNA 1, HGNC:49443) is a long non-coding RNA gene on chromosome 1p32.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49443
Approved symbol	DAB1-AS1
Name	DAB1 antisense RNA 1
Location	1p32.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226759
Ensembl biotype	lncRNA
Entrez	101926890
RNAcentral	URS0000D78063 — lncRNA, 1214 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 31 — 31 lncRNA

ENST00000416598, ENST00000420811, ENST00000432897, ENST00000434141, ENST00000457412, ENST00000585576, ENST00000585589, ENST00000586465, ENST00000587466, ENST00000588058, ENST00000588227, ENST00000590080, ENST00000591173, ENST00000591523, ENST00000591882, ENST00000592753, ENST00000592838, ENST00000592898, ENST00000608580, ENST00000608806, ENST00000608833, ENST00000609323, ENST00000610175, ENST00000610197, ENST00000627488, ENST00000628558, ENST00000628850, ENST00000667877, ENST00000829925, ENST00000829926, ENST00000829927

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416598 — 2 exons

Exon	Start	End
ENSE00001610227	57860532	57861033
ENSE00002805609	57862456	57863215

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 91.97.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0615 / max 57.7389, expressed in 4 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
3016	0.0322	3
3017	0.0233	4
3015	0.0060	3

Top tissues by expression

217 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	91.97	gold quality
right testis	UBERON:0004534	91.05	gold quality
testis	UBERON:0000473	88.99	gold quality
sperm	CL:0000019	86.04	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.75	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.43	gold quality
sural nerve	UBERON:0015488	70.38	gold quality
bone marrow cell	CL:0002092	69.48	silver quality
cortical plate	UBERON:0005343	65.03	gold quality
ventricular zone	UBERON:0003053	63.14	gold quality
adult organism	UBERON:0007023	62.39	silver quality
ganglionic eminence	UBERON:0004023	62.33	gold quality
corpus callosum	UBERON:0002336	57.90	gold quality
calcaneal tendon	UBERON:0003701	57.51	gold quality
monocyte	CL:0000576	56.53	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.49	gold quality
islet of Langerhans	UBERON:0000006	53.62	gold quality
buccal mucosa cell	CL:0002336	52.50	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.88	gold quality
gall bladder	UBERON:0002110	50.60	gold quality
muscle of leg	UBERON:0001383	50.37	gold quality
adrenal tissue	UBERON:0018303	50.32	gold quality
gastrocnemius	UBERON:0001388	49.34	gold quality
prefrontal cortex	UBERON:0000451	49.22	gold quality
tonsil	UBERON:0002372	48.55	silver quality
tendon	UBERON:0000043	48.39	silver quality
vermiform appendix	UBERON:0001154	47.95	gold quality
skin of hip	UBERON:0001554	47.83	silver quality
lymph node	UBERON:0000029	47.51	gold quality
lower lobe of lung	UBERON:0008949	47.03	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.68

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.