DANT1

Summary

DANT1 (DXZ4 associated non-coding transcript 1, proximal, HGNC:50863) is a long non-coding RNA gene on chromosome Xq23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50863
Approved symbol	DANT1
Name	DXZ4 associated non-coding transcript 1, proximal
Location	Xq23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229335
Ensembl biotype	lncRNA
OMIM	301001
Entrez	106029310
RNAcentral	URS0000BC4443 — lncRNA, 916 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000415394, ENST00000451869, ENST00000687301, ENST00000689706, ENST00000836545, ENST00000836546, ENST00000836547, ENST00000836548, ENST00000836549, ENST00000836550, ENST00000836551, ENST00000836552, ENST00000836553, ENST00000836554, ENST00000836555, ENST00000836556

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415394 — 3 exons

Exon	Start	End
ENSE00004256076	115904819	115905485
ENSE00004256086	115840837	115841078
ENSE00004256096	115842840	115843177

Expression profiles

Bgee: expression breadth broad, 98 present calls, max score 83.34.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0058 / max 1.3836, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
197341	0.0058	3

Top tissues by expression

98 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.34	gold quality
lower esophagus mucosa	UBERON:0035834	69.30	gold quality
bone marrow	UBERON:0002371	64.12	gold quality
calcaneal tendon	UBERON:0003701	63.85	gold quality
islet of Langerhans	UBERON:0000006	61.33	gold quality
monocyte	CL:0000576	61.12	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.65	gold quality
blood	UBERON:0000178	59.13	gold quality
tonsil	UBERON:0002372	57.78	gold quality
primary visual cortex	UBERON:0002436	55.80	gold quality
placenta	UBERON:0001987	55.76	gold quality
nucleus accumbens	UBERON:0001882	55.55	gold quality
vermiform appendix	UBERON:0001154	55.40	gold quality
esophagus mucosa	UBERON:0002469	54.86	gold quality
vagina	UBERON:0000996	54.62	gold quality
right uterine tube	UBERON:0001302	54.30	gold quality
liver	UBERON:0002107	53.98	gold quality
heart left ventricle	UBERON:0002084	53.94	gold quality
caudate nucleus	UBERON:0001873	53.90	gold quality
right lobe of liver	UBERON:0001114	53.43	gold quality
right atrium auricular region	UBERON:0006631	53.24	gold quality
heart	UBERON:0000948	53.21	gold quality
gastrocnemius	UBERON:0001388	53.14	gold quality
right hemisphere of cerebellum	UBERON:0014890	52.99	gold quality
cerebellar hemisphere	UBERON:0002245	52.98	gold quality
putamen	UBERON:0001874	52.87	gold quality
right lobe of thyroid gland	UBERON:0001119	52.81	gold quality
prefrontal cortex	UBERON:0000451	52.58	gold quality
frontal cortex	UBERON:0001870	52.26	gold quality
right frontal lobe	UBERON:0002810	52.24	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.