DANT2

Summary

DANT2 (DXZ4 associated non-coding transcript 2, distal, HGNC:50862) is a long non-coding RNA gene on chromosome Xq23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50862
Approved symbol	DANT2
Name	DXZ4 associated non-coding transcript 2, distal
Location	Xq23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235244
Ensembl biotype	lncRNA
OMIM	301004
Entrez	642776
RNAcentral	URS00008E39C7 — lncRNA, 336 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 50 — 50 lncRNA

ENST00000430756, ENST00000664164, ENST00000664355, ENST00000664453, ENST00000686602, ENST00000688552, ENST00000689580, ENST00000692054, ENST00000693570, ENST00000701509, ENST00000701608, ENST00000754588, ENST00000754589, ENST00000754590, ENST00000754591, ENST00000754592, ENST00000754593, ENST00000754594, ENST00000754595, ENST00000754596, ENST00000754597, ENST00000754598, ENST00000754599, ENST00000754600, ENST00000754601, ENST00000754602, ENST00000754603, ENST00000754604, ENST00000754605, ENST00000754606, ENST00000754607, ENST00000754608, ENST00000836435, ENST00000836436, ENST00000836437, ENST00000836438, ENST00000836439, ENST00000836440, ENST00000836441, ENST00000836442, ENST00000836443, ENST00000836444, ENST00000836445, ENST00000836446, ENST00000836447, ENST00000836448, ENST00000836449, ENST00000836450, ENST00000836451, ENST00000836452

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000430756 — 3 exons

Exon	Start	End
ENSE00001669229	115946386	115946456
ENSE00004255875	115917271	115919149
ENSE00004255883	115968961	115969146

Expression profiles

Bgee: expression breadth ubiquitous, 152 present calls, max score 81.58.

FANTOM5 (CAGE): breadth broad, TPM avg 2.6344 / max 56.8086, expressed in 868 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
200243	2.6344	868

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.58	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.25	gold quality
sural nerve	UBERON:0015488	79.92	gold quality
colonic epithelium	UBERON:0000397	78.57	gold quality
bone marrow cell	CL:0002092	78.11	gold quality
lower esophagus mucosa	UBERON:0035834	62.67	gold quality
right lobe of thyroid gland	UBERON:0001119	62.28	gold quality
adrenal tissue	UBERON:0018303	62.13	gold quality
medial globus pallidus	UBERON:0002477	61.01	silver quality
ganglionic eminence	UBERON:0004023	60.85	gold quality
cortical plate	UBERON:0005343	60.61	gold quality
stomach	UBERON:0000945	60.60	gold quality
right uterine tube	UBERON:0001302	60.24	gold quality
left lobe of thyroid gland	UBERON:0001120	60.06	gold quality
ventricular zone	UBERON:0003053	59.95	gold quality
body of stomach	UBERON:0001161	59.74	gold quality
apex of heart	UBERON:0002098	59.59	gold quality
thyroid gland	UBERON:0002046	59.58	gold quality
tonsil	UBERON:0002372	58.75	gold quality
corpus callosum	UBERON:0002336	58.70	gold quality
endothelial cell	CL:0000115	58.38	gold quality
calcaneal tendon	UBERON:0003701	58.19	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.78	gold quality
buccal mucosa cell	CL:0002336	57.32	gold quality
transverse colon	UBERON:0001157	57.23	gold quality
right hemisphere of cerebellum	UBERON:0014890	56.87	gold quality
cerebellar cortex	UBERON:0002129	56.74	gold quality
globus pallidus	UBERON:0001875	56.60	silver quality
cerebellar hemisphere	UBERON:0002245	56.57	gold quality
primary visual cortex	UBERON:0002436	56.47	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.28

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.