DCTN1-AS1

Summary

DCTN1-AS1 (DCTN1 antisense RNA 1, HGNC:44151) is a long non-coding RNA gene on chromosome 2p13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44151
Approved symbol	DCTN1-AS1
Name	DCTN1 antisense RNA 1
Location	2p13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237737
Ensembl biotype	lncRNA
Entrez	100189589
RNAcentral	URS0000D77F4C — lncRNA, 2359 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000412957, ENST00000416630, ENST00000418990, ENST00000426715, ENST00000427343, ENST00000437991, ENST00000664266, ENST00000664792

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412957 — 3 exons

Exon	Start	End
ENSE00001693672	74391989	74392896
ENSE00001746021	74385524	74385750
ENSE00001775559	74391478	74391615

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 95.43.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 1.9538 / max 158.6496, expressed in 104 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
21017	1.3747	99
21018	0.4787	90
21016	0.1004	61

Top tissues by expression

227 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
oviduct epithelium	UBERON:0004804	95.43	gold quality
buccal mucosa cell	CL:0002336	85.51	gold quality
primary visual cortex	UBERON:0002436	80.51	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.50	gold quality
bone marrow cell	CL:0002092	79.50	gold quality
prefrontal cortex	UBERON:0000451	79.49	gold quality
nucleus accumbens	UBERON:0001882	77.63	gold quality
Brodmann (1909) area 9	UBERON:0013540	76.11	gold quality
putamen	UBERON:0001874	75.68	gold quality
caudate nucleus	UBERON:0001873	75.48	gold quality
Brodmann (1909) area 23	UBERON:0013554	75.06	gold quality
frontal cortex	UBERON:0001870	74.49	gold quality
occipital lobe	UBERON:0002021	74.41	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	74.35	gold quality
neocortex	UBERON:0001950	74.09	gold quality
middle temporal gyrus	UBERON:0002771	73.02	gold quality
anterior cingulate cortex	UBERON:0009835	72.98	gold quality
cerebral cortex	UBERON:0000956	72.55	gold quality
right frontal lobe	UBERON:0002810	71.87	gold quality
forebrain	UBERON:0001890	71.37	gold quality
superior frontal gyrus	UBERON:0002661	70.07	gold quality
sural nerve	UBERON:0015488	69.95	gold quality
hypothalamus	UBERON:0001898	69.90	gold quality
Ammon’s horn	UBERON:0001954	69.69	gold quality
brain	UBERON:0000955	69.42	gold quality
entorhinal cortex	UBERON:0002728	69.38	gold quality
amygdala	UBERON:0001876	68.75	gold quality
postcentral gyrus	UBERON:0002581	68.68	gold quality
temporal lobe	UBERON:0001871	68.32	gold quality
cortical plate	UBERON:0005343	66.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.05

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.