DDC-AS1
geneOn this page
Summary
DDC-AS1 (DDC antisense RNA 1, HGNC:40171) is a long non-coding RNA gene on chromosome 7p12.1.
At a glance
- Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).
Identifiers
Gene identifiers
| Field | Value |
|---|---|
| HGNC ID | HGNC:40171 |
| Approved symbol | DDC-AS1 |
| Name | DDC antisense RNA 1 |
| Location | 7p12.1 |
| Locus type | RNA, long non-coding |
| Status | Approved |
| Ensembl gene | ENSG00000226122 |
| Ensembl biotype | lncRNA |
| Entrez | 100129427 |
| RNAcentral | URS0000261EA4 — lncRNA, 1776 nt, 1 organism(s) |
Gene structure
Transcript identifiers
Ensembl transcripts: 1 — 1 lncRNA
ENST00000454521
RefSeq mRNA: 0 — MANE Select: None
Canonical transcript exons
ENST00000454521 — 5 exons
| Exon | Start | End |
|---|---|---|
| ENSE00001622695 | 50531759 | 50531882 |
| ENSE00001626458 | 50541346 | 50541409 |
| ENSE00001643892 | 50539831 | 50540145 |
| ENSE00001651519 | 50539114 | 50539167 |
| ENSE00001700061 | 50542245 | 50543463 |
Expression profiles
Bgee: expression breadth broad, 17 present calls, max score 57.86.
Top tissues by expression
173 total, by Bgee expression score (0-100, higher = more expressed):
| Tissue | Anatomy ID | Expression score | Quality |
|---|---|---|---|
| right adrenal gland cortex | UBERON:0035827 | 57.86 | gold quality |
| right adrenal gland | UBERON:0001233 | 48.95 | gold quality |
| islet of Langerhans | UBERON:0000006 | 48.05 | gold quality |
| adult mammalian kidney | UBERON:0000082 | 46.52 | gold quality |
| adrenal cortex | UBERON:0001235 | 44.38 | gold quality |
| right lobe of liver | UBERON:0001114 | 43.66 | silver quality |
| pancreas | UBERON:0001264 | 43.39 | silver quality |
| skeletal muscle tissue of rectus abdominis | UBERON:0004511 | 43.37 | gold quality |
| adrenal gland | UBERON:0002369 | 43.20 | gold quality |
| secondary oocyte | CL:0000655 | 42.57 | gold quality |
| pharyngeal mucosa | UBERON:0000355 | 42.45 | gold quality |
| left adrenal gland cortex | UBERON:0035825 | 42.40 | gold quality |
| blood | UBERON:0000178 | 42.21 | gold quality |
| kidney | UBERON:0002113 | 42.08 | silver quality |
| heart left ventricle | UBERON:0002084 | 41.97 | gold quality |
| muscle of leg | UBERON:0001383 | 41.96 | silver quality |
| vastus lateralis | UBERON:0001379 | 41.89 | gold quality |
| quadriceps femoris | UBERON:0001377 | 41.84 | gold quality |
| duodenum | UBERON:0002114 | 41.64 | gold quality |
| bone marrow | UBERON:0002371 | 41.60 | gold quality |
| skeletal muscle tissue | UBERON:0001134 | 41.49 | gold quality |
| prefrontal cortex | UBERON:0000451 | 41.35 | gold quality |
| superficial temporal artery | UBERON:0001614 | 41.33 | gold quality |
| cardiac ventricle | UBERON:0002082 | 41.15 | gold quality |
| palpebral conjunctiva | UBERON:0001812 | 41.10 | gold quality |
| mucosa of paranasal sinus | UBERON:0005030 | 40.98 | gold quality |
| small intestine | UBERON:0002108 | 40.92 | gold quality |
| heart | UBERON:0000948 | 40.85 | gold quality |
| skin of abdomen | UBERON:0001416 | 40.81 | silver quality |
| mouth mucosa | UBERON:0003729 | 40.81 | gold quality |
Single-cell (SCXA)
Detected in 1 experiment(s), a significant marker in 0.
| Experiment | Marker? | Max mean expression |
|---|---|---|
| E-ANND-3 | no | 2.13 |
Regulation
Is transcription factor: no
Cross-species orthologs
0 orthologs
Protein
Non-coding RNA — no protein product; not a drug target.
Function
No curated pathway, Gene-Ontology, or interaction data.
Disease & clinical
No curated disease, variant, or cancer-driver associations.
Drugs & pharmacology
No drug or pharmacology data — not an established drug target.
Related Atlas pages
- Disease cohort memberships (association, not causation — diseases whose associated-gene cohort lists this gene; a subset are also under Associated diseases): aromatic L-amino acid decarboxylase deficiency