DDX59-AS1

Summary

DDX59-AS1 (DDX59 antisense RNA 1, HGNC:41094) is a long non-coding RNA gene on chromosome 1q32.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41094
Approved symbol	DDX59-AS1
Name	DDX59 antisense RNA 1
Location	1q32.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260088
Ensembl biotype	lncRNA
Entrez	101929224
RNAcentral	URS000075CDA6 — lncRNA, 750 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000568695, ENST00000835041, ENST00000835043, ENST00000835044, ENST00000835045

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000568695 — 3 exons

Exon	Start	End
ENSE00001982925	200690309	200690430
ENSE00002576725	200669507	200669622
ENSE00002618803	200693753	200694250

Expression profiles

Bgee: expression breadth ubiquitous, 148 present calls, max score 88.31.

FANTOM5 (CAGE): breadth broad, TPM avg 0.9888 / max 54.2742, expressed in 406 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
7653	0.8541	336
7652	0.1347	56

Top tissues by expression

235 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	88.31	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.48	silver quality
oviduct epithelium	UBERON:0004804	78.27	gold quality
sural nerve	UBERON:0015488	73.28	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.38	gold quality
ventricular zone	UBERON:0003053	64.46	gold quality
adrenal tissue	UBERON:0018303	64.16	gold quality
ganglionic eminence	UBERON:0004023	63.69	gold quality
bone marrow cell	CL:0002092	63.24	silver quality
right uterine tube	UBERON:0001302	61.46	gold quality
fallopian tube	UBERON:0003889	61.10	gold quality
nucleus accumbens	UBERON:0001882	60.81	gold quality
amygdala	UBERON:0001876	60.61	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	59.83	gold quality
anterior cingulate cortex	UBERON:0009835	59.62	gold quality
caudate nucleus	UBERON:0001873	59.03	gold quality
putamen	UBERON:0001874	59.00	gold quality
spinal cord	UBERON:0002240	58.49	gold quality
prefrontal cortex	UBERON:0000451	58.41	gold quality
gall bladder	UBERON:0002110	58.35	gold quality
cortical plate	UBERON:0005343	58.27	gold quality
substantia nigra	UBERON:0002038	58.05	gold quality
hypothalamus	UBERON:0001898	57.52	gold quality
stromal cell of endometrium	CL:0002255	57.01	gold quality
right frontal lobe	UBERON:0002810	56.95	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.92	gold quality
Brodmann (1909) area 9	UBERON:0013540	56.56	gold quality
midbrain	UBERON:0001891	56.28	gold quality
medial globus pallidus	UBERON:0002477	56.13	silver quality
neocortex	UBERON:0001950	55.76	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.72

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.