DENND2B-AS1

Summary

DENND2B-AS1 (DENND2B antisense RNA 1, HGNC:56176) is a long non-coding RNA gene on chromosome 11p15.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56176
Approved symbol	DENND2B-AS1
Name	DENND2B antisense RNA 1
Location	11p15.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255159
Ensembl biotype	lncRNA
Entrez	102724784
RNAcentral	URS0000759BB6 — lncRNA, 974 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000527725, ENST00000532930, ENST00000533843

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000527725 — 3 exons

Exon	Start	End
ENSE00002157068	8785401	8785462
ENSE00002158216	8787054	8787286
ENSE00002170360	8810077	8810231

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 82.48.

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.48	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.24	silver quality
colonic epithelium	UBERON:0000397	78.09	gold quality
tonsil	UBERON:0002372	73.52	gold quality
sural nerve	UBERON:0015488	71.00	gold quality
skeletal muscle tissue	UBERON:0001134	68.94	silver quality
urinary bladder	UBERON:0001255	68.72	gold quality
stromal cell of endometrium	CL:0002255	68.66	gold quality
calcaneal tendon	UBERON:0003701	65.51	gold quality
left testis	UBERON:0004533	65.47	gold quality
testis	UBERON:0000473	65.10	gold quality
adrenal tissue	UBERON:0018303	64.82	gold quality
bone marrow cell	CL:0002092	62.86	silver quality
uterine cervix	UBERON:0000002	62.23	gold quality
right testis	UBERON:0004534	62.21	gold quality
ventricular zone	UBERON:0003053	61.63	gold quality
liver	UBERON:0002107	61.32	silver quality
kidney	UBERON:0002113	60.37	gold quality
corpus callosum	UBERON:0002336	59.45	gold quality
bone marrow	UBERON:0002371	58.49	gold quality
monocyte	CL:0000576	56.47	gold quality
prefrontal cortex	UBERON:0000451	56.08	gold quality
lymph node	UBERON:0000029	54.36	gold quality
superior frontal gyrus	UBERON:0002661	54.36	gold quality
descending thoracic aorta	UBERON:0002345	54.28	gold quality
muscle of leg	UBERON:0001383	54.25	gold quality
adult mammalian kidney	UBERON:0000082	53.97	gold quality
lung	UBERON:0002048	53.96	gold quality
hindlimb stylopod muscle	UBERON:0004252	53.87	gold quality
stomach	UBERON:0000945	52.57	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.