DENND6A-AS1

Summary

DENND6A-AS1 (DENND6A antisense RNA 1, HGNC:41152) is a long non-coding RNA gene on chromosome 3p14.3.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41152
Approved symbol	DENND6A-AS1
Name	DENND6A antisense RNA 1
Location	3p14.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000239801
Entrez	106144528

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 92.64.

Top tissues by expression

125 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.64	gold quality
colonic epithelium	UBERON:0000397	85.89	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.44	gold quality
cortical plate	UBERON:0005343	72.01	gold quality
calcaneal tendon	UBERON:0003701	71.96	gold quality
ventricular zone	UBERON:0003053	70.64	gold quality
bone marrow	UBERON:0002371	69.99	gold quality
skeletal muscle tissue	UBERON:0001134	69.73	gold quality
ganglionic eminence	UBERON:0004023	68.93	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.79	gold quality
right testis	UBERON:0004534	68.17	gold quality
left testis	UBERON:0004533	67.48	gold quality
testis	UBERON:0000473	67.06	gold quality
muscle of leg	UBERON:0001383	65.79	gold quality
gastrocnemius	UBERON:0001388	65.39	gold quality
islet of Langerhans	UBERON:0000006	64.76	gold quality
monocyte	CL:0000576	64.69	gold quality
apex of heart	UBERON:0002098	63.01	gold quality
primary visual cortex	UBERON:0002436	62.86	gold quality
heart left ventricle	UBERON:0002084	62.66	gold quality
fundus of stomach	UBERON:0001160	61.98	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.15	gold quality
adrenal tissue	UBERON:0018303	60.90	gold quality
mucosa of stomach	UBERON:0001199	60.89	gold quality
heart	UBERON:0000948	60.86	gold quality
blood	UBERON:0000178	60.74	gold quality
descending thoracic aorta	UBERON:0002345	60.12	gold quality
placenta	UBERON:0001987	59.33	gold quality
right atrium auricular region	UBERON:0006631	59.22	gold quality
uterine cervix	UBERON:0000002	58.59	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.