DENND6A-DT

Summary

DENND6A-DT (DENND6A divergent transcript, HGNC:51592) is a long non-coding RNA gene on chromosome 3p14.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51592
Approved symbol	DENND6A-DT
Name	DENND6A divergent transcript
Location	3p14.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000241933
Ensembl biotype	lncRNA
Entrez	101929159
RNAcentral	URS00008B5DDA — lncRNA, 2974 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000465933

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000465933 — 2 exons

Exon	Start	End
ENSE00004151524	57693816	57696596
ENSE00004151525	57693179	57693342

Expression profiles

Bgee: expression breadth broad, 68 present calls, max score 87.15.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3498 / max 23.8964, expressed in 160 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
36996	0.3498	160

Top tissues by expression

68 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	87.15	silver quality
urinary bladder	UBERON:0001255	52.25	silver quality
bone marrow	UBERON:0002371	49.63	silver quality
islet of Langerhans	UBERON:0000006	49.21	gold quality
blood	UBERON:0000178	49.08	silver quality
pancreas	UBERON:0001264	47.15	gold quality
placenta	UBERON:0001987	46.97	silver quality
muscle of leg	UBERON:0001383	46.20	silver quality
gastrocnemius	UBERON:0001388	45.08	silver quality
saliva-secreting gland	UBERON:0001044	44.98	silver quality
gall bladder	UBERON:0002110	44.92	silver quality
amygdala	UBERON:0001876	44.70	silver quality
hindlimb stylopod muscle	UBERON:0004252	44.66	silver quality
lung	UBERON:0002048	44.44	silver quality
myometrium	UBERON:0001296	44.35	silver quality
granulocyte	CL:0000094	43.99	silver quality
adult mammalian kidney	UBERON:0000082	43.84	silver quality
tibial artery	UBERON:0007610	42.68	silver quality
body of pancreas	UBERON:0001150	42.63	silver quality
left coronary artery	UBERON:0001626	41.27	silver quality
esophagus	UBERON:0001043	41.13	silver quality
esophagus mucosa	UBERON:0002469	40.78	silver quality
heart left ventricle	UBERON:0002084	40.76	silver quality
left ovary	UBERON:0002119	40.72	silver quality
stomach	UBERON:0000945	40.69	silver quality
subcutaneous adipose tissue	UBERON:0002190	40.31	silver quality
adipose tissue	UBERON:0001013	39.94	silver quality
muscle layer of sigmoid colon	UBERON:0035805	39.92	silver quality
right atrium auricular region	UBERON:0006631	39.87	silver quality
cerebellar hemisphere	UBERON:0002245	39.66	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.