DEPDC1-AS1

Summary

DEPDC1-AS1 (DEPDC1 antisense RNA 1, HGNC:50592) is a long non-coding RNA gene on chromosome 1p31.3-p31.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50592
Approved symbol	DEPDC1-AS1
Name	DEPDC1 antisense RNA 1
Location	1p31.3-p31.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234264
Ensembl biotype	lncRNA
Entrez	101927220
RNAcentral	URS0000271D9B — lncRNA, 1247 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000428732

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000428732 — 3 exons

Exon	Start	End
ENSE00001725496	68529325	68529479
ENSE00001742658	68537632	68538627
ENSE00004245754	68496671	68496771

Expression profiles

Bgee: expression breadth broad, 46 present calls, max score 70.97.

Top tissues by expression

169 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	70.97	silver quality
ganglionic eminence	UBERON:0004023	58.51	gold quality
muscle of leg	UBERON:0001383	55.73	silver quality
upper lobe of lung	UBERON:0008948	54.98	silver quality
lower lobe of lung	UBERON:0008949	54.42	silver quality
monocyte	CL:0000576	51.22	silver quality
prefrontal cortex	UBERON:0000451	51.09	gold quality
ovary	UBERON:0000992	48.80	gold quality
lymph node	UBERON:0000029	48.70	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	47.50	gold quality
islet of Langerhans	UBERON:0000006	46.29	silver quality
vermiform appendix	UBERON:0001154	45.86	silver quality
tonsil	UBERON:0002372	45.18	gold quality
duodenum	UBERON:0002114	44.81	gold quality
buccal mucosa cell	CL:0002336	44.80	silver quality
Brodmann (1909) area 9	UBERON:0013540	44.71	silver quality
lung	UBERON:0002048	44.59	gold quality
pancreas	UBERON:0001264	43.95	silver quality
frontal cortex	UBERON:0001870	43.61	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
heart	UBERON:0000948	43.05	gold quality
neocortex	UBERON:0001950	42.85	silver quality
small intestine	UBERON:0002108	42.82	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
muscle tissue	UBERON:0002385	42.42	gold quality
esophagus	UBERON:0001043	42.05	silver quality
endometrium	UBERON:0001295	42.04	gold quality
heart left ventricle	UBERON:0002084	41.97	gold quality
esophagus mucosa	UBERON:0002469	41.76	silver quality
skeletal muscle tissue	UBERON:0001134	41.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.