DHCR24-DT

Summary

DHCR24-DT (DHCR24 divergent transcript, HGNC:53969) is a long non-coding RNA gene on chromosome 1p32.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53969
Approved symbol	DHCR24-DT
Name	DHCR24 divergent transcript
Location	1p32.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	ESSENCE
Ensembl gene	ENSG00000233203
Ensembl biotype	lncRNA
Entrez	107984958
RNAcentral	URS0002A20893 — lncRNA, 1609 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000415336, ENST00000433690, ENST00000436033, ENST00000443284, ENST00000455380, ENST00000689429, ENST00000715513, ENST00000715515, ENST00000715516, ENST00000715517, ENST00000715518, ENST00000715519

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415336 — 2 exons

Exon	Start	End
ENSE00001644115	54887688	54888397
ENSE00001705870	54886860	54887135

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 88.39.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right testis	UBERON:0004534	88.39	gold quality
left testis	UBERON:0004533	87.64	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.51	gold quality
testis	UBERON:0000473	87.26	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.81	gold quality
adrenal tissue	UBERON:0018303	68.47	gold quality
lower esophagus mucosa	UBERON:0035834	68.00	gold quality
islet of Langerhans	UBERON:0000006	66.50	gold quality
liver	UBERON:0002107	65.47	gold quality
gall bladder	UBERON:0002110	65.20	gold quality
esophagus mucosa	UBERON:0002469	63.50	gold quality
left adrenal gland	UBERON:0001234	63.46	gold quality
adrenal gland	UBERON:0002369	63.29	gold quality
right lobe of liver	UBERON:0001114	63.06	gold quality
left adrenal gland cortex	UBERON:0035825	62.84	gold quality
prefrontal cortex	UBERON:0000451	62.57	gold quality
right adrenal gland	UBERON:0001233	62.36	gold quality
skin of abdomen	UBERON:0001416	62.24	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	61.71	gold quality
placenta	UBERON:0001987	61.69	gold quality
pancreas	UBERON:0001264	61.30	gold quality
body of stomach	UBERON:0001161	61.22	gold quality
ectocervix	UBERON:0012249	61.22	gold quality
zone of skin	UBERON:0000014	60.85	gold quality
stromal cell of endometrium	CL:0002255	60.71	gold quality
stomach	UBERON:0000945	60.38	gold quality
duodenum	UBERON:0002114	60.38	gold quality
skin of leg	UBERON:0001511	59.65	gold quality
lymph node	UBERON:0000029	59.50	gold quality
descending thoracic aorta	UBERON:0002345	59.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.