DHCR7-DT

Summary

DHCR7-DT (DHCR7 divergent transcript, HGNC:56822) is a long non-coding RNA gene on chromosome 11q13.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56822
Approved symbol	DHCR7-DT
Name	DHCR7 divergent transcript
Location	11q13.4
Locus type	RNA, long non-coding
Status	Approved
Aliases	AP, lnc, AP002387.2, RP11-660L16.2
Ensembl gene	ENSG00000254682
Ensembl biotype	lncRNA
Entrez	129810502
RNAcentral	URS00026A1A63 — lncRNA, 826 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000529369

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000529369 — 2 exons

Exon	Start	End
ENSE00004106772	71451690	71452165
ENSE00004106773	71448542	71448885

Expression profiles

Bgee: expression breadth ubiquitous, 136 present calls, max score 97.37.

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	97.37	gold quality
thymus	UBERON:0002370	88.68	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.70	gold quality
pituitary gland	UBERON:0000007	84.04	gold quality
spinal cord	UBERON:0002240	83.96	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	83.95	gold quality
nucleus accumbens	UBERON:0001882	83.78	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	83.75	gold quality
adenohypophysis	UBERON:0002196	83.72	gold quality
amygdala	UBERON:0001876	83.68	gold quality
temporal lobe	UBERON:0001871	83.64	gold quality
right hemisphere of cerebellum	UBERON:0014890	83.39	gold quality
cerebellar hemisphere	UBERON:0002245	83.25	gold quality
hindlimb stylopod muscle	UBERON:0004252	83.17	gold quality
cerebellum	UBERON:0002037	83.12	gold quality
cerebellar cortex	UBERON:0002129	83.09	gold quality
granulocyte	CL:0000094	83.02	gold quality
substantia nigra	UBERON:0002038	82.69	gold quality
quadriceps femoris	UBERON:0001377	82.60	gold quality
body of pancreas	UBERON:0001150	82.59	gold quality
putamen	UBERON:0001874	82.39	gold quality
mucosa of transverse colon	UBERON:0004991	82.37	gold quality
Ammon’s horn	UBERON:0001954	82.33	gold quality
blood	UBERON:0000178	82.28	gold quality
anterior cingulate cortex	UBERON:0009835	82.00	gold quality
brain	UBERON:0000955	81.88	gold quality
pancreas	UBERON:0001264	81.73	gold quality
hypothalamus	UBERON:0001898	81.73	gold quality
islet of Langerhans	UBERON:0000006	81.18	gold quality
Brodmann (1909) area 9	UBERON:0013540	81.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.78

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.